Novel technology for the fast production of complex nanoliposomes

Effect of liposomal complexes of quercetin-rich flavonoids from French Marigold (Tagetes patula L.) on Jurkat cell viability

“…Quercetin is highly soluble in lipids and alcohol, but it is not very soluble in water[28], the quercetin molecule can bind to hydrophobic parts of the liposomes and can also be incorporated into the internal volume (lumen) of the liposomes. Quercetin-rich flavonoid fraction extracted from a French Marigold (Tagetes patula L.) was placed inside liposomes in complexes prepared by the method described byMdzinarashvili et al, (2016) [29]. To equalize the liposome diameters (200 nm), the suspension of complex liposomes was finally extruded through a nanoporous membrane[29].Statistics:To evaluate the statistical credibility of the influence of different effects on cell viability, and the differences between the treated and control groups, a pairwise comparison using Student's t-test was performed.…”

“…Quercetin-rich flavonoid fraction extracted from a French Marigold (Tagetes patula L.) was placed inside liposomes in complexes prepared by the method described byMdzinarashvili et al, (2016) [29]. To equalize the liposome diameters (200 nm), the suspension of complex liposomes was finally extruded through a nanoporous membrane[29].Statistics:To evaluate the statistical credibility of the influence of different effects on cell viability, and the differences between the treated and control groups, a pairwise comparison using Student's t-test was performed. The values of ≤0.001, ≤0.01, and ≤0.05 were designated as highly significant, significant, and marginally significant, respectively.…”