Novel β-cyclodextrin doped carbon dots for host–guest recognition-assisted sensing of isoniazid and cell imaging

Abstract

Novel β-cyclodextrin (β-CD) doped carbon dots (CCDs) were prepared at a mild temperature to preserve the host–guest recognition properties of β-CD. An isoniazid fluorescence sensor was constructed with a limit of detection of 0.14 μg mL−1.

Bioinspired Carbon Dots-Based Fluorescent Sensor for the Selective Determination of a Potent Anti-Inflammatory Drug in the Presence of Its Photodegradation Products

“…Furthermore, we compared the absorption spectrum of tangerine seeds extract with that of the resulting CDs, as shown in Figure a, a strong peak was clearly observed at 320 nm in the absorption spectrum of the prepared CDs which may be attributed to the n -π* transition of the functional groups present on CDs, on the other hand, no observable peak could be found in the absorption spectrum of tangerine seeds extract at 320 nm. The obtained results prove the successful formation of CDs. , The FI of the prepared biogenic CDs depends on the excitation wavelength across the 310–380 nm range (Figure b). The developed biogenic CDs have a maximum FI centered at λ em = 404 nm after their maximum excitation at λ ex = 320 nm.…”

“…Moreover, the function groups that attached to the surface of the prepared biogenic CDs were characterized by FT-IR and compared with that of the precursor (tangerine seeds extract). The comparison of the two FT-IR spectra (Figure 2d), revealed that the prepared biogenic CDs retained the same function groups of the precursor, most importantly the oxygen rich function groups. These results confirmed that there are plenty of oxygen-rich groups attached to the surfaces of the prepared biogenic CDs.…”

“…33 Moreover, the function groups that attached to the surface of the prepared biogenic CDs were characterized by FT-IR and compared with that of the precursor (tangerine seeds extract). The comparison of the two FT-IR spectra (Figure 2d), revealed that the prepared biogenic CDs retained the same function groups of the precursor, 34 S3) and 0.371, respectively. The high negative value of zeta potential (−23 mv) 35,36 provides stability to the prepared CDs as the repulsion between the negatively charged CDs inhibits their aggregation, in addition to the resulted value of PDI indicates the narrow particle size distribution of the prepared CDs.…”

Coatings of Cyclodextrin/Citric-Acid Biopolymer as Drug Delivery Systems: A Review

“…It is important to mention that CD/CTR polymers have not only been used as drug-delivery systems, but other interesting applications have also been studied, such as the removal of pollutants in water of heavy metal ions [ 76 , 77 ], dyes [ 78 , 79 ], organic compounds [ 78 , 79 , 80 ], and other things. Most recently, CD/CTR has also been utilized for host–guest recognition in sensors of herbicides [ 81 ] and antibiotics [ 82 ].…”

Self-Assembly of Cyclodextrin-Coated Nanoparticles:Fabrication of Functional Nanostructures for Sensing and Delivery

“…Cyclodextrin-based nano-containers have been immobilized onto various nanoparticle surfaces to provide a handle for specific interaction. Although not addressed in this article, it should be noted that the discrete CD-coated nanoparticles are interesting functional platforms and have been utilized in applications such as chemical sensors, drug delivery, and catalysis [ 15 , 16 , 17 , 18 , 19 , 20 ] ( Scheme 1 ). The focus of this review is to survey the utilization of CD-coated nanoparticles as building blocks toward the design and construction of various structural and functional self-assembled structures.…”