Nuclear cardiology

Anagnostopoulos, Constantinos; Underwood, S. Richard

doi:10.7861/clinmedicine.12-4-373

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…Traditionally, nuclear imaging, nuclear therapy, and radiopharmaceutical technologies were mainly used in research laboratories. However, they are now routinely used in clinical practice for diagnosis, prognosis, and prediction of various diseases, especially in oncology, 1 , 2 cardiology, 3 , 4 neurology, 5 and infectious and inflammatory disorders. 6 This change can be attributed to advances in nuclear imaging technologies for improving image quality and spatial resolution, 7 as well as the development of more economically feasible ways of preparing and measuring radiopharmaceuticals.…”

Section: Introductionmentioning

confidence: 99%

Emulsion Technology in Nuclear Medicine: Targeted Radionuclide Therapies, Radiosensitizers, and Imaging Agents

Winuprasith¹,

Koirala²,

McClements³

et al. 2023

IJN

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Radiopharmaceuticals serve as a major part of nuclear medicine contributing to both diagnosis and treatment of several diseases, especially cancers. Currently, most radiopharmaceuticals are based on small molecules with targeting ability. However, some concerns over their stability or non-specific interactions leading to off-target localization are among the major challenges that need to be overcome. Emulsion technology has great potential for the fabrication of carrier systems for radiopharmaceuticals. It can be used to create particles with different compositions, structures, sizes, and surface characteristics from a wide range of generally recognized as safe (GRAS) materials, which allows their functionality to be tuned for specific applications. In particular, it is possible to carry out surface modifications to introduce targeting and stealth properties, as well as to control the particle dimensions to manipulate diffusion and penetration properties. Moreover, emulsion preparation methods are usually simple, economic, robust, and scalable, which makes them suitable for medical applications. In this review, we highlight the potential of emulsion technology in nuclear medicine for developing targeted radionuclide therapies, for use as radiosensitizers, and for application in radiotracer delivery in gamma imaging techniques.

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Section: Introductionmentioning

confidence: 99%

Emulsion Technology in Nuclear Medicine: Targeted Radionuclide Therapies, Radiosensitizers, and Imaging Agents

Winuprasith¹,

Koirala²,

McClements³

et al. 2023

IJN

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COVID‐19 and nuclear cardiology: Introducing the “forward” virtual visit

2020

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Harnessing the Heart’s Magnetic Field for Advanced Diagnostic Techniques

Elfouly,

Alouani

2024

Sensors

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Heart diseases remain one of the leading causes of morbidity and mortality worldwide, necessitating innovative diagnostic methods for early detection and intervention. An electrocardiogram (ECG) is a well-known technique for the preliminary diagnosis of heart conditions. However, it can not be used for continuous monitoring due to skin irritation. It is well known that every body organ generates a magnetic field, and the heart generates peak amplitudes of about 10 to 100 pT (measured at a distance of about 3 cm above the chest). This poses challenges to capturing such signals. This paper reviews the different techniques used to capture the heart’s magnetic signals along with their limitations. In addition, this paper provides a comprehensive review of the different approaches that use the heart-generated magnetic field to diagnose several heart diseases. This research reveals two aspects. First, as a noninvasive tool, the use of the heart’s magnetic field signal can lead to more sensitive advanced heart disease diagnosis tools, especially when continuous monitoring is possible and affordable. Second, its current use is limited due to the lack of accurate, affordable, and portable sensing technology.

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Nuclear cardiology

Cited by 3 publications

References 19 publications

Emulsion Technology in Nuclear Medicine: Targeted Radionuclide Therapies, Radiosensitizers, and Imaging Agents

Emulsion Technology in Nuclear Medicine: Targeted Radionuclide Therapies, Radiosensitizers, and Imaging Agents

COVID‐19 and nuclear cardiology: Introducing the “forward” virtual visit

Harnessing the Heart’s Magnetic Field for Advanced Diagnostic Techniques

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