Nuclear magnetic resonance spectra of lanostane derivatives

1,11-Iminoestrones. II. Derivatives and reactions

“…17 ppm (s,. M ethyl 9,10-Dihydro-4,5-imino-7-methoxy-2-methylphenanthrene 1-Acetate (7).-To a solution of the methyl ester (6b, 21 mg, 0.048 mmole) in 10 ml of methylene chloride was added 84 mg (1.5 mmoles) of potassium hydroxide dissolved in 25 ml of methanol. The solution was allowed to stand at room temperature for 1 hr, then acidified with acetic acid, and evaporated in the presence of toluene.…”

“…However, it appears likely that this reaction may proceed via the expected 19-acetoxyandrosta-l,4,7-trien-3-one (iv) which then gives v on alkaline hydrolysis. J>DQ, dioxane 17-hr NaOH, CHaOH ture (7). In the mass spectrum of 7, the molecular ion (M+) was the base peak and occurred at m/e 309 (caled for C19H19NO3, 309).…”

“…(7) H. Budzikiewicz, C. Djerassi, and D. H. Williams, "Structure and Elucidation of Natural Products by Mass Spectrometry," Vol. I, Holden-Day, Inc., San Francisco, Calif., 1964, pp 42,53-57.…”

New Triterpenes from the Bark of Western White Pine (Pinus monticola DOUGL.)

“…Recrystallization from benzene afforded an analytical sample of 3~-methoxy-25,26,27-trinor-5a-lanostan-24-al (3), m.p. [180][181][a#= + 43.7" (c=0.6,CHCI3). -IR.…”

Formation of A/B cis- and trans-19-norlanosterols by enzymic cyclization of 6'-norsqualene 2,3-oxide

“…This is the same within error as the increase shown by a dilute DPPH solution under these conditions (2.84). 13 The color of pure 1 is not visibly changed at -196°.…”