In order to investigate the safety and stability of loess high slope under dynamic ramming, the MatDem software was used to simulate the process of heavy rammer compacting the spot which was 11 m away from the toe of loess high slope. The rammer was applied with different energies of 10000 kN·m, 8000 kN·m, and 6000 kN·m. In this way, the safety and stability of slope under the action of different dynamic tamping energies can be determined. The results show that the loess high slope presented circular landslide damage by dynamic compaction. Under the same ramming times, with the decrease of ramming energy, the damage degree of loess high slope gradually reduced. According to the displacement value of different monitoring points, the large horizontal and vertical displacement points in landslide were obtained. When the ramming energy was 10000 kN·m and 8000 kN·m, the maximum horizontal displacements were 15.45 m and 10.72 m, and the maximum vertical displacements were 17.43 m and 11.91 m. When the ramming energy was 6000 kN·m, the soil at the bottom of slope would produce slight vibration. Considering the actual project, when the ramming energy was 10000 kN·m and 8000 kN·m, the minimum safe distance was recommended to be 25 m and 20 m. When the ramming energy was 6000 KN·m, the slope remained stable as a whole, and the minimum safe distance suggested should not be less than 11 m. A safety distance of collapse of loess high slope under dynamic compaction was determined, which provided a strong safety guidance for loess high slope construction under dynamic compaction.