Numerical Simulation and Experiments of Two Fiber Optical Tweezers

Zhongfu, 吴忠福 Wu; Zhihai, 刘志海 Liu; Chengkai, 郭成凯 Guo; Jun, 杨军 Yang; Libo, 苑立波 Yuan

doi:10.3788/aos20082810.1971

Cited by 1 publication

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“…When the electromagnetic field is stably distributed, the second term on the left side of Equation ( 1) is zero. The total force of the electromagnetic field acting in the V region is equal to the area integral of the Maxwell stress tensor at the interface [36,37]. Figure 2 shows the light field distribution and optical force of light capture on the two-dimensional plane.…”

Section: Electromagnetic Theory Modelmentioning

confidence: 99%

Optical Manipulation of Fibroblasts with Femtosecond Pulse and CW Laser

Zhang,

Wu,

Cai

et al. 2024

Photonics

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Using tight focusing light, optical tweezers (OT) are tools that can manipulate and capture microscopic particles and biological cells as well as characterize a wide range of micro and nanomaterials. In this paper, we focused on fibroblasts, which are widely used in the biomedical area for a variety of purposes, including promoting human wound healing and preventing the early proliferation of tumor cells. We first built an optical tweezer experimental platform, using an 808 nm continuous-wave laser as the capture light source, to confirm that the device can precisely control the movement of single or multiple particles as well as fibroblasts. Then, a 1030 nm femtosecond laser was employed as the capture light source to study the manipulation of microparticles and fibroblasts at different powers. Lastly, a protracted manipulation protocol was used to prevent the fibroblasts from adhering to the wall. This method can be used to isolate and precisely block adherent growth of fibroblasts in cell populations. This experimental result can be further extended to other biological cells.

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Section: Electromagnetic Theory Modelmentioning

confidence: 99%