Numerical simulation of flow fields in a tube with two branches

Lee, Denz; Chen, J. Y.

doi:10.1016/s0021-9290(00)00083-x

Cited by 17 publications

(7 citation statements)

References 12 publications

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“…In such area, a stagnant fluid behaviour is predicted near the lateral walls of both side branches. It should be noted that the results were found to be both quantitatively and qualitatively consistent with other studies (Berthier et al, 2002;Lee et al, 2000). …”

Section: Velocity Profilessupporting

confidence: 91%

Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: Steady state simulations

Politis

Stavropoulos

Christolis

et al. 2007

Journal of Biomechanics

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Section: Velocity Profilessupporting

confidence: 91%

Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: Steady state simulations

Politis

Stavropoulos

Christolis

et al. 2007

Journal of Biomechanics

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“…This amounts to about 64,000 grids in the junction alone and the total number of grid was about one million. If necessary, zonal or adaptive gridding methods which locally enhance the grid density developed by the authors 33,34 can be considered for better resolution. Performance comparison of all types of mixers in this study was based on the simulation with the same grid size.…”

Section: Numerical Aspectsmentioning

confidence: 99%

Mixing in tangentially crossing microchannels

Lee

Chen

2011

AIChE Journal

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In this study, we have demonstrated that effective mixing can be achieved in simple and regular crossing channels. The dynamical processes combining split-and-recombine and chaotic mixing elements of stretching and folding were discussed. In channels with simple turns (up/down/right/left), flow could be stretched; on the other hand, tangential crossings could yield folding. Theoretically, repeating stretching and folding then result in the increase of interfacial area and decrease of striation thickness which facilitate the eventual mixing by diffusion. Practically, the structural sequence of turning and/or crossing affects the performance of the mixing. Three types of micromixers were studied, and the simulated performance was favorably compared with the published data. Experiments were carried out to qualitatively demonstrate the typical performance in the mixers.

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“…11 Another emerging tool for exploring the aortic hemodynamic flowfield is numerical simulations performed by the computational fluid dynamics (CFD) code. 17,20,[23][24][25][26][27]29,30,35,38,46 Nevertheless, most of the above described numerical studies of the aortic flow have placed emphasis on elucidating the relationship between the complex flow field in the thoracic aorta and the pathogenesis of atherosclerosis and aneurysms. 17,27,35 The correlation between the hemodynamic factors and the thoracic aorta dissection is seldom discussed.…”

Section: Introductionmentioning

confidence: 99%

Investigation of Pulsatile Flowfield in Healthy Thoracic Aorta Models

et al. 2009

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Cardiovascular disease is the primary cause of morbidity and mortality in the western world. Complex hemodynamics plays a critical role in the development of aortic dissection and atherosclerosis, as well as many other diseases. Since fundamental fluid mechanics are important for the understanding of the blood flow in the cardiovascular circulatory system of the human body aspects, a joint experimental and numerical study was conducted in this study to determine the distributions of wall shear stress and pressure and oscillatory WSS index, and to examine their correlation with the aortic disorders, especially dissection. Experimentally, the Phase-Contrast Magnetic Resonance Imaging (PC-MRI) method was used to acquire the true geometry of a normal human thoracic aorta, which was readily converted into a transparent thoracic aorta model by the rapid prototyping (RP) technique. The thoracic aorta model was then used in the in vitro experiments and computations. Simulations were performed using the computational fluid dynamic (CFD) code ACE+((R)) to determine flow characteristics of the three-dimensional, pulsatile, incompressible, and Newtonian fluid in the thoracic aorta model. The unsteady boundary conditions at the inlet and the outlet of the aortic flow were specified from the measured flowrate and pressure results during in vitro experiments. For the code validation, the predicted axial velocity reasonably agrees with the PC-MRI experimental data in the oblique sagittal plane of the thoracic aorta model. The thorough analyses of the thoracic aorta flow, WSSs, WSS index (OSI), and wall pressures are presented. The predicted locations of the maxima of WSS and the wall pressure can be then correlated with that of the thoracic aorta dissection, and thereby may lead to a useful biological significance. The numerical results also suggest that the effects of low WSS and high OSI tend to cause wall thickening occurred along the inferior wall of the aortic arch and the anterior wall of the brachiocephalic artery, similar implication reported in a number of previous studies.

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Numerical simulation of flow fields in a tube with two branches

Cited by 17 publications

References 12 publications

Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: Steady state simulations

Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: Steady state simulations

Mixing in tangentially crossing microchannels

Investigation of Pulsatile Flowfield in Healthy Thoracic Aorta Models

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