Numerical simulation of the position and orientation effects on the impedance response of nanoelectrode array biosensors to DNA and PNA strands

Capacitive biosensing of bacterial cells: Analytical model and numerical simulations

“…The DL capacitance C DL also slightly increases since the Debye length D is shortened by larger charge repulsion. At higher frequencies, the charges do not impact Y/ω , as expected from previous works reporting the impact of DNA charges only at low frequency in [35]. When considering the sensitivity S(ω), the bump around 10 kHz is drastically lowered by v,b because of the smaller influence of Table 1 are used.…”

“…For the ion-penetrable bacterial cell wall, the ionic diffusion coefficient is assumed 40% of the one of the surrounding electrolyte [26]. The ion transport is described by the Nernst-Planck equation [20,34,35]:…”

Derivation and Numerical Verification of a Compact Analytical Model for the AC Admittance Response of Nanoelectrodes, Suitable for the Analysis and Optimization of Impedance Biosensors

“…(2)-(3)) described in [15] and [16]. Compared to [15], [16], a more accurate description of the typical nanoelectrode array geometry (see Fig.…”

“…Compared to [15], [16], a more accurate description of the typical nanoelectrode array geometry (see Fig. 1(c)) was achieved by defining two ringshaped counter-electrodes at the bottom of the simulation domain (see Fig.…”

“…This planar arrangement of the electrodes generates a highly non uniform distribution of the electric field in the electrolyte over the extension of the particle, especially at low frequency approximately up to the electrolyte cut-off frequency σ b /ε b . Therefore, differently from [15], [16] where electrodes were located one in front of the other (see Fig. 1(a)), the improved simulation code used in this work is suited to check if the assumption of field uniformity made in the derivation of Eq.…”