Nutraceuticals in Prophylaxis and Therapy of Neurodegenerative Diseases

Pallavi, Madhurantakam C. Preethi; Kumar, Halmuthur M. Sampath

doi:10.1016/b978-0-12-809593-5.00008-2

Cited by 6 publications

(7 citation statements)

References 34 publications

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“…There are several propsed neuroprotective properties for piperine including improved neurodegeneration and memory impairment. Studies have shown that piperine administration in rats improved the function of memory and protected against the degeneration of hippocampal ( Mythri et al, 2012 ; Preethi Pallavi et al, 2018 ). Correia et al, (2015) examined the neuroprotective effect of piperine(5 and 10 mg/kg for 2 weeks) on PD in an animal model of rats.…”

Section: Black Pepper ( Piper Nigrum (L) [Piperace...mentioning

confidence: 99%

From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders

et al. 2022

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Aging is described as an advanced time-related collection of changes that may negatively affect with the risk of several diseases or death. Aging is a main factor of several age-related neurological disorders, including neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, and dementia), stroke, neuroinflammation, neurotoxicity, brain tumors, oxidative stress, and reactive oxygen species (ROS). Currently available medications for age-related neurological disorders may lead to several side effects, such as headache, diarrhea, nausea, gastrointestinal (GI) diseases, dyskinesia, and hallucinosis. These days, studies on plant efficacy in traditional medicine are being conducted because herbal medicine is affordable, safe, and culturally acceptable and easily accessible. The Indian traditional medicine system called Ayurveda uses several herbs and medicinal plants to treat various disorders including neurological disorders. This review aims to summarize the data on the neuroprotective potential of the following common Indian spices widely used in Ayurveda: cumin (Cuminum cyminum (L.), Apiaceae), black cumin (Nigella sativa (L.), Ranunculaceae), black pepper (Piper nigrum (L.), Piperaceae), curry leaf tree (Murraya koenigii (L.), Spreng Rutaceae), fenugreek (Trigonella foenum-graecum (L.), Fabaceae), fennel (Foeniculum vulgare Mill, Apiaceae), cardamom (Elettaria cardamomum (L.) Maton, Zingiberaceae), cloves (Syzygium aromaticum (L.) Merr. & L.M.Perry, Myrtaceae), and coriander (Coriandrum sativum (L.), Apiaceae) in age-related neurological disorders.

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Section: Black Pepper ( Piper Nigrum (L) [Piperace...mentioning

confidence: 99%

From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders

et al. 2022

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“…They also prevent the activation of NF-kB, which further prevents the activation of proinflammatory cytokines, mainly interleukins. It is among the most commonly explored phytoconstituents, mainly obtained from the leaf extract of Gingko biloba , in the prevention and cure of cognitive disorders [ 64 ]. They are also highly effective in improving the circulation of blood in the brain and prevent the progression of Alzheimer’s disease [ 65 ].…”

Section: Nutraceuticals In Ameliorating Neurodegenerationmentioning

confidence: 99%

“…Malondialdehyde is a by-product formed post peroxidation of lipids which acts as an utmost important marker for the detection of free radicals of oxidative stress-mediated neurodegeneration. Asiatic acid increases the levels of free radical scavenging enzymes, such as glutathione, and augments its antioxidant medication protection of neurodegeneration [ 64 ].…”

Section: Nutraceuticals In Ameliorating Neurodegenerationmentioning

confidence: 99%

“…Ingredients of the Mediterranean diet, such as coffee, extra virgin olive oil, walnuts, etc., also improve memory and are highly beneficial. The phenolic compounds extracted from plants are highly emphasized as they possess maximum therapeutic benefits [ 64 ].…”

Section: Nutraceuticals In Ameliorating Neurodegenerationmentioning

confidence: 99%

“…Table 2. Summary of the nutraceuticals discussed in the current review with their mode of action and specific disease activity [64,82,83].…”

Section: Nutraceuticals In Psychotic Disordersmentioning

confidence: 99%

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Nutraceuticals in Neurological Disorders

Makkar

Behl

Bungău

et al. 2020

IJMS

130

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Neurological diseases are one of the major healthcare issues worldwide. Posed lifestyle changes are associated with drastically increased risk of chronic illness and diseases, posing a substantial healthcare and financial burden to society globally. Researchers aim to provide fine treatment for ailing disorders with minimal exposed side effects. In recent decades, several studies on functional foods have been initiated to obtain foods that have fewer side effects and increased therapeutic activity. Hence, an attempt has been made to unravel several extraction techniques to acquire essential bioactive compounds or phytochemicals from therapeutically active food products. This has led to the conception of the term functional foods being meddled with other similar terms like “pharmafoods,” “medifoods”, “vitafoods”, or “medicinal foods”. With a dire need to adhere towards healthy options, the demand of nutraceuticals is widely increasing to combat neurological interventions. An association between food habits and the individual lifestyle with neurodegeneration has been manifested, thereby proposing the role of nutraceuticals as prophylactic treatment for neurological interventions. The current review covers some of the major neurological disorders and nutraceutical therapy in the prevention of disease.

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Fruits and Nutraceuticals for the Prevention and Treatment of Central Nervous System Disorders

Sayed

Egbuna

2023

Phytochemical Drug Discovery for Central Nervous System Disorders

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Nutraceuticals in Prophylaxis and Therapy of Neurodegenerative Diseases

Cited by 6 publications

References 34 publications

From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders

From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders

Nutraceuticals in Neurological Disorders

Fruits and Nutraceuticals for the Prevention and Treatment of Central Nervous System Disorders

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