Nutrients and Nutraceuticals in Aging

Hodjat, Mahshid; Khalid, Madiha; Asghari, Majid; Atri, S H; Rahimifard, Mahban; Nejad, Solmaz Mohammadi; Baeeri, Maryam

doi:10.1007/978-981-15-3552-9_5

Cited by 3 publications

(1 citation statement)

References 272 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other nutraceuticals, including multivitamins, minerals such as zinc, selenium, and magnesium, fish oils, etc., also help in the improvement of cognitive functions in various domains [40,[43][44][45][46][47].…”

Section: Effects Of Nutraceuticals In Cognitive Aging and Progression...mentioning

confidence: 99%

Perspective Chapter: Nutraceuticals as a Therapeutic Promise in Healthy Aging and Neurocognitive Disorders

Ramesh¹,

Banerjee²

2023

Geriatric Medicine and Healthy Aging

View full text Add to dashboard Cite

The world is facing a rapid population ageing. Noncommunicable disorders (NCDs) form the bulk of present-day morbidity. Besides dealing with neurodegeneration and neurocognitive disorders, modern-day therapeutics have also geared toward healthy ageing and preventive approaches. Several chemical substances belonging to classes of natural dietary origin display protective properties against some age-related diseases, including neurodegenerative ones. These compounds, known as nutraceuticals, differ structurally, acting on different pathways. There has been a paradigm shift in the understanding of dementias toward neuroinflammation, oxidative stress, immunomodulation, and gut-brain axis dysregulation. This offers promise for the nutraceuticals as a novel approach in the field of neurocognitive disorders and healthy ageing. However, the collective evidence is still evolving and as of yet not robust enough for nutraceuticals to be a part of clinical guidelines. The other caveats are lack of subjective understanding of use, and individual constituents of a product showing differential effects, which lead to ambiguous outcomes in clinical trials. This chapter critically looks at the role of various nutraceuticals in promoting healthy aging and management of neurodegenerative conditions (especially Alzheimer’s disease). The evidence so far is highlighted with the challenges in their use and future directions of research.

show abstract

Section: Effects Of Nutraceuticals In Cognitive Aging and Progression...mentioning

confidence: 99%

Perspective Chapter: Nutraceuticals as a Therapeutic Promise in Healthy Aging and Neurocognitive Disorders

Ramesh¹,

Banerjee²

2023

Geriatric Medicine and Healthy Aging

View full text Add to dashboard Cite

show abstract

Enhancing the bioavailability of encapsulated hydrophobic nutraceuticals: Insights from in vitro, in vivo, and clinical studies

Abuhassira-Cohen

2022

Current Opinion in Food Science

View full text Add to dashboard Cite

Exploring the Geroprotective Potential of Nutraceuticals

Rivero-Segura,

Zepeda-Arzate,

Castillo-Vazquez

et al. 2024

Nutrients

View full text Add to dashboard Cite

Aging is the result of the accumulation of a wide variety of molecular and cellular damages over time, meaning that “the more damage we accumulate, the higher the possibility to develop age-related diseases”. Therefore, to reduce the incidence of such diseases and improve human health, it becomes important to find ways to combat such damage. In this sense, geroprotectors have been suggested as molecules that could slow down or prevent age-related diseases. On the other hand, nutraceuticals are another set of compounds that align with the need to prevent diseases and promote health since they are biologically active molecules (occurring naturally in food) that, apart from having a nutritional role, have preventive properties, such as antioxidant, anti-inflammatory and antitumoral, just to mention a few. Therefore, in the present review using the specialized databases Scopus and PubMed we collected information from articles published from 2010 to 2023 in order to describe the role of nutraceuticals during the aging process and, given their role in targeting the hallmarks of aging, we suggest that they are potential geroprotectors that could be consumed as part of our regular diet or administered additionally as nutritional supplements.

show abstract

Nutrients and Nutraceuticals in Aging

Cited by 3 publications

References 272 publications

Perspective Chapter: Nutraceuticals as a Therapeutic Promise in Healthy Aging and Neurocognitive Disorders

Perspective Chapter: Nutraceuticals as a Therapeutic Promise in Healthy Aging and Neurocognitive Disorders

Enhancing the bioavailability of encapsulated hydrophobic nutraceuticals: Insights from in vitro, in vivo, and clinical studies

Exploring the Geroprotective Potential of Nutraceuticals

Contact Info

Product

Resources

About