Nutrigenomics: DNA-based individualized nutrition

Abstract

In the past decade, nutrition research has undergone an important shift from epidemiology and physiology to molecular biology, adipobiology and genetics, thus launching the science of nutrigenomics. To at molecular level study effects of nutrition on health and disease. The completion of several large genome projects has markedly altered the research agenda by drawing attention to the importance of genes in human nutrition. There has been a growing recognition that micronutrients and macronutrients can be potent dietary signals that influence the metabolic pathways of cells and have an important role in the control of energy, vascular and neuronal homeostasis. Accordingly, nutrition researchers have increasingly started to recognize that gene-environment interactions can be implicated in the pathogenesis of lifestyle-related diseases, particularly cardiometabolic diseases, fatty liver diseases, cancers, and Alzheimer' disease. An adiponutrigenomic insight into life expectancy is also outlined. Overall, the present Dance Round focuses on a mater of nationwide importance for Bulgaria, a country at the epicenter of today's global healthquake, the obesity and related diseases.

Adipobiology: a scientometric view to its increasing significance

“…They should be provided to young researchers and university faculty in order to promote their efforts for meeting the increasing social and biomedical requirements of today and the future. In effect, adipobiology will be associated with adipopharmacology (16)(17)(18), nutrigenomics (19) and other related research fields. The future of adipobiology research comprises a much more intensive differentiation and integration of the problem circles, of propagation of ideas and methods into problem-oriented, mono-, two-, multi-and interdisciplinary branches of the holistic knowledge of purposeful promotion of human health and effective prediction and prevention of disease as well as a paradigm of science globalization.…”

Homo obesus: A Metabotrophin-Deficient Species. Pharmacology and Nutrition Insight

“…Altogether, such an intellectual growth process open new areas of many "-omics" sciences such as nutrigenomics, proteomics, metabolomics and adipomics. Nutrigenomics addresses the nutrient-induced gene and protein expression relative to either prevention/therapy or pathogenesis of various diseases, including obesity/CMD [31,32].…”