“…In a retrospective study, Bellon et al (2019), compared the results of the so-called Hamburg modification of Frey's operation; as a result, the advantages of such an operation over other duodenalpreserving resections of the pancreatic head were revealed; exo-, endocrine function of a pancreas did not differ from the point of view of control of a pain syndrome and the life quality (Konstantinidis et al, 2010). At the same time, the authors pointed out two important findings, namely: continued alcohol intake after surgery was significantly associated with relapse of pain; there was no reliable data on the duration of chronic pancreatitis, it was noted that almost all patients had terminal disease stage (Bellon et al, 2019;Yarmukhamedova et al, 2021;Lestari et al, 2021;Widana et al, 2020). In 2012, Dutch researchers have concluded that although the choice of the surgery based on pathological anatomical changes allows obtaining results of pain control in chronic pancreatitis from excellent to satisfactory ones, however, an early Surgery intervention performed before many endoscopic treatment attempts and the need for strong analgesics may (Wilcox et al, 2014), where no reliable relationship was found between the findings and the presence and severity of pain by comparing the surveys of patients and their imaging data.…”