Nutritional components and physiological activities of Petasites japonicus solvent extracts

Abstract

Petasites japonicus (PJ) has been used traditionally as the treatment or the prophylaxis of migraine and tension headache in Asia. In the present study, to we compared the characteristics of PJ powder and extracts obtained by various methods utilize the PJ as a functional material. PJ powder by freeze-drying possessed 6.61% water content, 4.51% crude fat, 23.75% crude protein, 18.62% crude ash, 46.97% carbohydrates, and crude fiber 39.22%. It contained a particularly high potassium content in mineral. Among different extraction methods, extracts of 50% (PJ-50E) or 70% ethanol (PJ-70E) showed the highest total polyphenol content and antioxidant activity, while cold-water extraction (PJ-WE) showed the lowest. However, when the α-glucosidase inhibitory were analyzed, PJ-WE was highest while the treatment extracted ethanol were not active at all. In anti-inflammatory activity by RAW 264.7 and HaCaT cells, PJ-WE showed significantly higher inhibitory activity in comparison to those of the other extract. In conclusion, it is considered that the water-extraction method is better than other extraction methods for practical preparation of functional materials with high α-glucosidase inhibitory and anti-inflammatory activities from PJ.

Short-Term Effects of PJE Administration on Metabolic Parameters in Diet-Induced Obesity Mice

“…Maxim.) is a perennial herbaceous plant belonging to the Asteraceae family that grows naturally in wild wetlands, and it grows wild not only in China and Japan, but also in Korea, from Jeju Island to the central region [ 10 ]. In folk remedies or oriental medicine, dried sprouts were boiled in water and used for coughing, bronchial asthma, and treatment of poisoning [ 11 ].…”

“…Maxim., caffeic acid, 3-O-caffeoylquinic acid, fukinolic acid in flowers, and petasinophenol, flavonoid glycosides, phenylprophenoyl sulfonic acid, and fukinolic acid in leaves were detected as antioxidant compounds [ 11 , 12 , 13 ]. In addition, sesquiterpene esters such as petasin and s-petasin, which have anti-asthmatic and anti-allergic effects in leaves, backkenolide B, and petatewalide B with anti-allergic and anti-inflammatory effects in leaves were isolated [ 10 ]. Analysis of active components such as petasin and some phenolics from P. japonicus (Siebold & Zucc.)…”