Nutritional Genomics - An Overview of CRISPR/Cas9 Genome Editing System on Nutraceuticals

Abstract

Nutraceuticals have gained popularity for supplemental health benefits and for the ability to complement pharmaceuticals to prevent, delay, and manage chronic disease. The development of nutraceuticals involves the use of genome editing technology such as the newly developed CRISPR/Cas9 system, a novel and powerful method to knock out, knock-in, upregulate, and downregulate genes, including genes that can improve the nutritional profile of a plant as well as increase the production of nutraceuticals. Nutraceuticals, such as those implicated in aging, life expectancy, and chronic diseases can now be developed using CRISPR/Cas9. Establishing a CRISPR-based system to develop nutraceuticals and improve human health will benefit society.