2021
DOI: 10.1093/bjs/znab282.009
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O4 Neural network image capture to predict response of oesophageal adenocarcinoma to neoadjuvant therapy

Abstract: Introduction Locally advanced oesophageal adenocarcinoma is typically treated with neoadjuvant chemotherapy (NACT) or chemoradiotherapy (NACRT) followed by surgery. Significant benefit to neoadjuvant treatment however is confined to a minority of patients (<25%) and there are no reliable means of establishing prior to treatment in whom this benefit will occur. In this study, we assessed the utility of features extracted from high-resolution digital microscopy of pre-treatment biopsies … Show more

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