2008
DOI: 10.1007/s00535-007-2128-7
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Obesity as a risk factor for GERD in Japan

Abstract: Both GERD prevalence and the prevalence of hernia were significantly higher in obese subjects, and the prevalence of GERD in subjects who had gained weight was also significantly higher. From these results, it was concluded that obesity is a risk factor for GERD in Japan.

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Cited by 53 publications
(51 citation statements)
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“…Lifestyle factors, such as eating foods with high components of fat or in large portions, alcohol intake, smoking, obesity, and metabolic syndrome, have also been reported to be related to a high prevalence of reflux esophagitis and GERD symptoms (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). In addition, the factors shown to induce and/or worsen GERD have also been demonstrated to be associated with periodontitis.…”
Section: Discussionmentioning
confidence: 99%
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“…Lifestyle factors, such as eating foods with high components of fat or in large portions, alcohol intake, smoking, obesity, and metabolic syndrome, have also been reported to be related to a high prevalence of reflux esophagitis and GERD symptoms (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). In addition, the factors shown to induce and/or worsen GERD have also been demonstrated to be associated with periodontitis.…”
Section: Discussionmentioning
confidence: 99%
“…An increased gastroesophageal pressure gradient and hiatal hernia development have been reported to be induced by a high intra-abdominal pressure due to abdominal fat accumulation (3)(4)(5)(6)(7), while obesity and a high body mass index (BMI) have repeatedly been demonstrated to be associated with the high prevalence of reflux esophagitis and GERD symptoms (8)(9)(10)(11)(12)(13)(14)(15). In addition, metabolic syndrome, diagnosed by the presence of visceral fat accumulation, dyslipidemia, hypertension, and hyperglycemia, has been demonstrated to correlate with the occurrence of GERD (16)(17)(18).…”
Section: Introductionmentioning
confidence: 99%
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“…[3][4][5][6] There are many opinions on the relationship between obesity and GERD; for example, obesity is a risk factor for GERD. 7 However, we found no relationship between body mass index and esophageal dysfunction in our patients (unpublished data). The duration of diabetes and autonomic neuropathy may infl uence the pathophysiology of esophageal dysfunction in patients with diabetes.…”
Section: Authors' Replymentioning
confidence: 48%
“…In the study of Sakaguchi et al (32), weight gain was defined as gaining 2 kilos in the last 2 months and losing weight was defined as losing 2 kilos in the last 2 months. According to this definition, a higher prevalence of GERD was determined in those who gained weight in the end of 2 months in comparison to those with no weight change or who lost weight in the end of 2 months (p<0.005).…”
Section: Does a Decrease Occur In The Severity And Development Of Gasmentioning
confidence: 99%