Obesity Is a Risk Factor for Significant Carotid Atherosclerosis in Patients Aged 39 to 55 Years

Silva, Erasmo Simão da; Giglio, Pedro Nogueira; Waisberg, Daniel Reis; Filho, Richard Geraldo Jaqueta; Casella, Ivan Benaduce; Puech-Leão, Pedro

doi:10.1177/0003319713494753

Cited by 12 publications

(8 citation statements)

References 34 publications

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“…Our results indicate that age, gender, and diabetes significantly affect the prevalence of CA. Other studies reported hypercholesterolemia, 18 obesity, 19 hypertension, 20 and other factors to be additional risk factors associated with CA. However, as shown in this study, these factors were only associated with the prevalence of CA in either men or women and showed no significant correlation with the prevalence of CA in the overall population.…”

Section: Discussionmentioning

confidence: 94%

Factors Significantly Associated With the Increased Prevalence of Carotid Atherosclerosis in a Northeast Chinese Middle-aged and Elderly Population

Pan

Lai

et al. 2016

Medicine

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Carotid atherosclerosis is associated with many serious cardiovascular diseases; hence, it is necessary to identify factors related to its occurrence in order to develop preventive and therapeutic strategies. This study was conducted to identify risk factors associated with carotid atherosclerosis among the population residing in Northeast China.This epidemiological survey was conducted in a representative group of relatively healthy community residents. All participants answered questions about their medical histories and underwent physical examination, blood biochemical analysis, and ultrasonography examinations of their necks and abdomens. The prevalence rates of carotid atherosclerosis under different factors and conditions were then analyzed.The results of this study showed that age, gender, and diabetes significantly affected the prevalence of carotid atherosclerosis in this Northeast Chinese population. In addition, gender-based subgroup analysis revealed additional factors correlated with the prevalence of carotid atherosclerosis in men or women, although their correlations were not significant in the overall population. While high serum TC and LDL-C levels were risk factors for carotid atherosclerosis in men, it showed no clear correlation with the prevalence of carotid atherosclerosis in women. In contrast, the prevalence of carotid atherosclerosis in female participants with high serum TG level, hypertension, obesity and nonalcoholic fatty liver disease were higher than that of the control population, a trend not observed in male participants.Older age, male sex, and diabetes were independently associated with increased risk of carotid atherosclerosis in Northeast China. These findings could lead to improved screening for carotid atherosclerosis for better disease management.

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Section: Discussionmentioning

confidence: 94%

Factors Significantly Associated With the Increased Prevalence of Carotid Atherosclerosis in a Northeast Chinese Middle-aged and Elderly Population

Pan

Lai

et al. 2016

Medicine

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“…[51] In another study, higher BMI was a risk factor for significant carotid atherosclerosis (higher rate of occlusion and near occlusion) in the patients aged 39 to 55 years. [52]…”

Section: Discussionmentioning

confidence: 99%

Prevalence of extracranial carotid atherosclerosis in the patients with coronary artery disease in a tertiary hospital in Malaysia

Sahadevan¹,

Chee²,

Tai

2019

Medicine

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There is limited information regarding the prevalence of extracranial carotid atherosclerosis in the patients with coronary artery disease (CAD) undergoing coronary artery bypass graft (CABG) surgery in South East Asia. The primary objective was to assess the prevalence of extracranial carotid stenosis, raised carotid intima media thickness (CIMT), and plaques in the patients with CAD undergoing elective CABG. The secondary objective was to evaluate the risk factors for extracranial carotid atherosclerosis. A total of 119 consecutive patients with CAD undergoing elective CABG in a tertiary hospital in Malaysia were recruited. Data on the demographic characteristics and risk factors were collected. The ultrasound carotid Doppler findings comprising of raised CIMT, plaques, and stenosis in the extracranial carotid vessels were recorded. The mean age of the patients was 64.26 ± 10.12 (range 42–89). Most of the patients were men (73.1%). The patients consisted of 44 (37%) Malays, 26 (21.8%) Chinese, and 49 (41.2%) Indians. A total of 67 (56.3%) patients had raised CIMT, 89 (74.8%) patients had plaques, and 10 (8.4%) patients had stenosis in the internal and common carotid arteries. The mean age of patients with plaques was higher compared to those without plaques (66.00 ± 9.63 vs 59.10 ± 9.92, P = .001). The body mass index (BMI) of patients with stenosis was higher compared to those without stenosis (28.35 ± 4.92 vs 25.75 ± 3.16, P = .02). The patients with plaques were more likely to be older, whereas the patients with carotid stenosis were more likely to have higher BMI.

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“…Khambet et al (8) reported values for sensitivity of 76% and specificity of 99% for DPR detecting calcified carotid artery atheromatous plaques. With this in mind we aimed to analyse the relation The risk factors for atherosclerosis, according to the literature, coincide with cardiovascular disease (13), such as increasing age (14), history of stroke, hypertension, diabetes, smoking, hypercholesterolemia (1,6,9,11,12,14), alcohol consumption (4,15) and obesity (16). Zheng et al (15) reported statistical significance between alcohol consumption in a population with atherosclerosis and cardiovascular accidents.…”

Section: Discussionmentioning

confidence: 99%

Assessment of carotid calcifications on digital panoramic radiographs: Retrospective analysis and review of the literature

Monteiro

Ibrahim²,

Albuquerque

et al. 2018

Journal of Stomatology, Oral and Maxillofacial Surgery

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Obesity Is a Risk Factor for Significant Carotid Atherosclerosis in Patients Aged 39 to 55 Years

Cited by 12 publications

References 34 publications

Factors Significantly Associated With the Increased Prevalence of Carotid Atherosclerosis in a Northeast Chinese Middle-aged and Elderly Population

Factors Significantly Associated With the Increased Prevalence of Carotid Atherosclerosis in a Northeast Chinese Middle-aged and Elderly Population

Prevalence of extracranial carotid atherosclerosis in the patients with coronary artery disease in a tertiary hospital in Malaysia

Assessment of carotid calcifications on digital panoramic radiographs: Retrospective analysis and review of the literature

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