Objective and Quantitative Improvement of Rosacea-Associated Erythema After Intense Pulsed Light Treatment

Mark, Kenneth A.; Sparacio, Rose Marie; Voigt, Audra; Marenus, K.; Sarnoff, Deborah S

doi:10.1046/j.1524-4725.2003.29141.x

Cited by 65 publications

(60 citation statements)

References 14 publications

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“…Given the correlation between facial skin rosacea and MGD, it seems plausible that treatment of skin rosacea might also improve MGD. Intense pulsed light (IPL) has demonstrated good clinical efficacy in skin rosacea 10,11. Could that type of treatment somehow benefit MGD as well?…”

Section: Introductionmentioning

confidence: 99%

Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction

Dell¹,

Gaster²,

Barbarino³

et al. 2017

OPTH

121

115

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PurposeThe aim of this study was to estimate the efficacy of intense pulsed light (IPL), followed by meibomian gland expression (MGX), for reducing the number and severity of signs and symptoms of dry eye disease (DED) secondary to meibomian gland dysfunction (MGD).Patients and methodsIn a prospective study conducted in two sites, 40 subjects (80 eyes) with moderate to severe MGD were enrolled. Major inclusion criteria consisted of at least two of the following measures being compatible with DED in both eyes: tear breakup time (TBUT), meibomian gland score (MGS), corneal fluorescein staining (CFS), Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire, and tear film osmolarity (TFO). Enrolled patients underwent four treatment sessions, 3 weeks apart. Each treatment included the administration of 10–15 pulses of IPL on the cheeks and nose, followed by MGX of the upper and lower eyelids. TBUT, MGS, CFS, SPEED, TFO, and lipid layer thickness (LLT) were measured at baseline (BL) and at 9, 12, and 15 weeks after BL.ResultsDue to different staining methods used for TBUT measurements, TBUT and CFS were analyzed separately for each site. From BL to the final follow-up, the number of signs compatible with DED decreased from 3.3±0.1 to 1.4±0.1. TBUT improved by +93% (n=38; P<0.0001) and +425% (n=42; P<0.0001) for sites 1 and 2, respectively. SPEED, MGS, and CFS improved by −55% (n=80; P<0.0001), −36% (n=80; P<0.0001), and −58% (n=38; P<0.0001), respectively. In 20 eyes with abnormally elevated TFO at BL, TFO improved by −7% (n=20; P<0.005). LLT did not change (n=38; P=0.88).ConclusionIn subjects with moderate to severe MGD, IPL combined with MGX reduced the number and severity of symptoms and signs of DED. Except for LLT, all examined outcome measures significantly improved after 15 weeks. These results support the efficacy of IPL + MGX in relieving both signs and symptoms of DED secondary to MGD.

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Section: Introductionmentioning

confidence: 99%

Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction

Dell¹,

Gaster²,

Barbarino³

et al. 2017

OPTH

121

115

View full text Add to dashboard Cite

show abstract

“…By their speed progress, they are becoming more effective with lesser complication rates. [1][2][3][4][5][15][16][17] However, they are safe and effective, and these systems are expensive and need complex instruments. Because of disadvantages, sometimes clinicians need alternative methods for the treatment of the facial telangiectasias.…”

Section: Discussionmentioning

confidence: 99%

Using Silicone Gel Sheet for the Treatment of Facial Telangiectasias With Sclerotherapy

et al. 2004

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“…Therefore, due to its very impressive effect on flushing and dilated vessels, intense pulsed light (IPL) and laser treatment should finally be an established part of dermatological therapy regimen [19][20][21][22][23][24].…”

Section: Stadium III or Severe Rosaceamentioning

confidence: 99%

Management of rosacea with intense pulsed light (IPL) systems and laser

Kautz

2008

Medical Laser Application

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Objective and Quantitative Improvement of Rosacea-Associated Erythema After Intense Pulsed Light Treatment

Abstract: As demonstrated by truly objective and quantitative means, intense pulsed light is effective for reducing rosacea-associated blood flow, telangiectasia, and erythema.

Cited by 65 publications

References 14 publications

Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction

Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction

Using Silicone Gel Sheet for the Treatment of Facial Telangiectasias With Sclerotherapy

Management of rosacea with intense pulsed light (IPL) systems and laser

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