Observation of ionic desorption channels in cluster-induced desorption of alkali halides – Influence of surface electronic properties and surface configuration

Soft cluster-induced desorption and ionization of biomolecules—Influence of surface load and morphology on desorption efficiency

“…This is seen as an indicator that film constitution, especially residual water molecules in the film, may play an important role for an efficient desorption and ionization process, similar to the results found for the desorption of alkali halides. 20 FIG. 4.…”

Desorption/ionization induced by neutral cluster impact as a soft and efficient ionization source for ion trap mass spectrometry of biomolecules

“…We would like to discuss our results first with respect to the desorption and ionization of DSPC and rhodamine molecules. To date, DINeC experiments have been restricted to oligopeptides and alkali halides . With the desorption and ionization of a phospholipid and dye molecules, two new classes of molecules are shown to be accessible by desorption and ionization induced by neutral cluster impact thus demonstrating the more general applicability of DINeC as an ion source for chemical analysis by means of mass spectrometry.…”

“…To date, DINeC experiments have been restricted to oligopeptides and alkali halides. [9,10,[12][13][14] With the desorption and ionization of a phospholipid and dye molecules, two new classes of molecules are shown to be accessible by desorption and ionization induced by neutral cluster impact thus demonstrating the more general applicability of DINeC as an ion source for chemical analysis by means of mass spectrometry. and (c), the main peak (m/z 443) of the initial spectrum was isolated and fragmented by means of CID.…”

“…Shattering of the cluster during and after surface impact then leads to a rapid redistribution of the system's energy thus avoiding heating and fragmentation of the desorbing molecules . Ions may be formed either through charge transfer in the sample solution if the charge prevails on the surface or in the cluster during cluster‐surface impact; in the case of oligopeptides, the dominant ions are cations of the form [M + H] + .…”

Quantification of the ionization probability during desorption/ionization of oligopeptides induced by neutral cluster impact

“…[15] Predominantly, positive ions of the form [M + H] + are observed. Ions may be formed either through charge transfer in the original solution if the charge prevails on the surface [18] or during cluster-surface impact. [16,17] In this contribution, quantification of the ionization efficiency Z, i.e., the ion-to-neutral ratio of the DINeC process, is described.…”