Observations from a six month study on the effect of biodegradation processes in sediment on the toxicity potential of targeted chemicals

Dutka, B. J.; Liu, D.; Jurkovic, A.; McInnis, R.; Lee, H.-B.; Onuska, Francis I.; Rao, S. Narasimha

doi:10.1002/(sici)1098-2256(1998)13:4<313::aid-tox4>3.0.co;2-a

Environ. Toxicol. Water Qual.

1998

DOI: 10.1002/(sici)1098-2256(1998)13:4<313::aid-tox4>3.0.co;2-a

|View full text |Cite

Observations from a six month study on the effect of biodegradation processes in sediment on the toxicity potential of targeted chemicals

B. J. Dutka¹,

D. Liu²,

A. Jurkovic³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2005

2008

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies indicate that further degradation is possible under aerobic conditions (5,6,8,26,31). Two bacteria that are able to degrade 4-nonylphenol efficiently and use it as a sole carbon and energy source have recently been isolated from activated sludge (9,28).…”

mentioning

confidence: 99%

Differential Degradation of Nonylphenol Isomers by Sphingomonas xenophaga Bayram

Gabriel

Giger

Guenther

et al. 2005

Appl Environ Microbiol

106

118

View full text Add to dashboard Cite

Sphingomonas xenophaga Bayram, isolated from the activated sludge of a municipal wastewater treatment plant, was able to utilize 4-(1-ethyl-1,4-dimethylpentyl)phenol, one of the main isomers of technical nonylphenol mixtures, as a sole carbon and energy source. The isolate degraded 1 mg of 4-(1-ethyl-1,4-dimethylpentyl)phenol/ml in minimal medium within 1 week. Growth experiments with five nonylphenol isomers showed that the three isomers with quaternary benzylic carbon atoms [(1,1,2,4-tetramethylpentyl)phenol, 4-(1-ethyl-1,4-dimethylpentyl)phenol, and 4-(1,1-dimethylheptyl)phenol] served as growth substrates, whereas the isomers containing one or two hydrogen atoms in the benzylic position [4-(1-methyloctyl)phenol and 4-nnonylphenol] did not. However, when the isomers were incubated as a mixture, all were degraded to a certain degree. Differential degradation was clearly evident, as isomers with more highly branched alkyl side chains were degraded much faster than the others. Furthermore, the C 9 alcohols 2,3,5-trimethylhexan-2-ol, 3,6-dimethylheptan-3-ol, and 2-methyloctan-2-ol, derived from the three nonylphenol isomers with quaternary benzylic carbon atoms, were detected in the culture fluid by gas chromatography-mass spectrometry, but no analogous metabolites could be found originating from 4-(1-methyloctyl)phenol and 4-n-nonylphenol. We propose that 4-(1-methyloctyl)phenol and 4-n-nonylphenol were cometabolically transformed in the growth experiments with the mixture but that, unlike the other isomers, they did not participate in the reactions leading to the detachment of the alkyl moiety. This hypothesis was corroborated by the observed accumulation in the culture fluid of an as yet unidentified metabolite derived from 4-(1-methyloctyl)phenol.

show abstract

mentioning

confidence: 99%

Differential Degradation of Nonylphenol Isomers by Sphingomonas xenophaga Bayram

Gabriel

Giger

Guenther

et al. 2005

Appl Environ Microbiol

106

118

View full text Add to dashboard Cite

show abstract

Investigating the Estrogenic Risk Along the River Po and Its Intermediate Section

Viganò

Mandich

Benfenati

et al. 2006

Arch Environ Contam Toxicol

View full text Add to dashboard Cite

Different endpoints have been used to investigate the occurrence of estrogenic risk along the Po River, particularly its middle section. An in vitro assay based on recombinant yeast could not detect estrogenic activity in bed sediments of the Italian river or in bile samples of five Cyprinid species, with the only exception being one carp (Cyprinus carpio) captured downstream of the River Lambro, a polluted tributary of the middle River Po. Chemical analyses of fish bile and water samples from the same middle section showed diffuse contamination by moderately low levels of estrogenic chemicals (estrone [E1], 17beta-estradiol, estriol [E3], 17alpha-ethinylestradiol, 4-nonylphenol [NP], 4-tert-octylphenol [tOP], 4-n-octylphenol, and bisphenol A) but they were of limited help in understanding the risk present in the downstream area where intersex barbel were previously found. In contrast, the analyses of River Lambro waters showed that this tributary is a source to the middle River Po of all eight estrogens investigated. Analyses of bed sediments and macroinvertebrates from the same area consistently showed at least two levels of contamination, with the downstream stretch showing higher concentrations of natural steroids (E1 and E3) and xenoestrogens (NP and tOP). Accordingly, new histologic examinations undertaken on young barbel (Barbus sp.) showed intersex gonads only in the individuals captured in the downstream stretch, thereby confirming previous results. Present findings confirm the occurrence of disrupting conditions in the middle River Po and provide the first suggestions of cause-effect relationships.

show abstract

C8- and C9-Alkylphenols and Ethoxylates: II. Assessment of Environmental Persistence and Bioaccumulation Potential

Klečka

Staples²,

Naylor

et al. 2008

Human and Ecological Risk Assessment: An International Journal

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Observations from a six month study on the effect of biodegradation processes in sediment on the toxicity potential of targeted chemicals

Cited by 3 publications

References 12 publications

Differential Degradation of Nonylphenol Isomers by Sphingomonas xenophaga Bayram

Differential Degradation of Nonylphenol Isomers by Sphingomonas xenophaga Bayram

Investigating the Estrogenic Risk Along the River Po and Its Intermediate Section

C8- and C9-Alkylphenols and Ethoxylates: II. Assessment of Environmental Persistence and Bioaccumulation Potential

Contact Info

Product

Resources

About