The use of comfort systems, the number of which in vehicles is constantly increasing, has a direct impact on fuel consumption and engine load. As part of the article, the vehicle's drive in real operating conditions was analyzed in terms of the emission of toxic compounds. The tests were carried out without and with the systems turned on, using the PEMS apparatus, where road emissions of carbon dioxide, carbon monoxide, hydrocarbons, nitrogen oxides and solid particles were measured in terms of mass, number and size distribution of diameters. The track was driven four times with different setting of the powertrain of examined car.