2024
DOI: 10.1002/cnm.3826
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Observer‐based control for plasma glucose regulation in type 1 diabetes mellitus patients with unknown input delay

Boubekeur Targui,
Jose‐Fernando Castro‐Gomez,
Omar Hernández‐González
et al.

Abstract: This article introduces an observer‐based control strategy tailored for regulating plasma glucose in type 1 diabetes mellitus patients, addressing challenges like unknown time‐varying delays and meal disturbances. This control strategy is based on an extended Bergman minimal model, a nonlinear glucose‐insulin model to encompass unknown inputs, such as unplanned meals, exercise disturbances, or delays. The primary contribution lies in the design of an observer‐based state feedback control in the presence of unk… Show more

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