I would like to take the 'Marathon' as the metaphor to describe my PhD journey. I'd say the experience 'on the road' is valuable and unforgettable to me. People might say that the starting point, which way you will select to go and where you start, is very important. Yes, I definitely agree. However, I want to leave most of my words to the running process here. Trial and error, making adjustments and modifications, pains and gains are all the necessary and beautiful (complex mood to say this word) scenery along the journey. You have to experience and learn how to enjoy and overcome them. Luckily, I am not lonely. Many people are to be appreciated here.First and foremost, I would like to express my sincere thanks to my promoter Prof. Dr. Bob Su, who initializes this running project and provides me with the message "there is a very interesting research topic I would like you to contribute something!". Your critical thinking, rich experience, continuous support and warming encouraging words, "Enjoy the journey! Cherish the person! Good health!", like the lighthouse, inspire me to keep on track and stand up from the failures and then move forward.