Obsevations on the Clinical Use of Radio Pills

Am, Connell; McCall, John E.; Jj, Misiewicz; En, Rowlands

doi:10.1136/bmj.2.5360.771

Cited by 33 publications

(11 citation statements)

References 6 publications

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“…Intraluminal pressures were measured on the right side of the colon using a radiotelemetering capsule (Connell, McCall, Misiewicz, and Rowlands, 1963). Frequency modulated signals were picked up by a multidirectional aerial resting lightly on the abdomen, with a Solartron radio receiver connected to a pen writer.…”

Section: Methodsmentioning

confidence: 99%

Postoperative motility of the large intestine in man.

Wilson¹

1975

Gut

139

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SUMMARY Motor activity of the colon in the immediate postoperative period has been studied in human subjects using radiotelemetering capsules, radioopaque markers and serial abdominal radiographs.Following operations outside the abdomen there is a delay of about 16 hours before colonic activity returns. After abdominal operations the delay is from 40 to 48 hours.The length of an operation has no significant effect upon the duration of colonic ileus. The amount of postoperative analgesia has no significant effect upon the duration of colonic ileus. Gaseous distension after laparotomy is confined to the colon.It is well recognized that following operation the motility of the gastrointestinal tract is temporarily impaired. At times this is more prolonged and, if associated with gaseous distension, develops into paralytic ileus. It has been shown in experimental animals that the activity of the small intestine returns to normal within a few hours following surgery (Tinckler, 1965;Baker and Webster, 1968). Early return of activity has also been shown in man using a radiotelemetering capsule (Ross, Watson, and Kay, 1963 (Nachlas, Younis, Roda, and Wityk, 1972;Neely, 1968). Most of these studies have been radiological observations of barium in the gastrointestinal tract, and, althoughthestudies have been primarily directed at the stomach, most workers have observed that barium is also held up in the colon. Study of the colon has not been taken further than this one observation.The present study investigates in more detail the motor behaviour of the colon in the postoperative

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Section: Methodsmentioning

confidence: 99%

Postoperative motility of the large intestine in man.

Wilson¹

1975

Gut

139

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“…27,28,64,65 It is indicated for detection of generalized dysmotility or as part of evaluation of WGTT.…”

Section: Wireless Motility Capsulementioning

confidence: 99%

Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology and Motility Societies

Rao¹,

Camilleri²,

Hasler³

et al. 2010

Neurogastroenterology &Amp; Motility

326

296

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Background Disorders of gastrointestinal (GI) transit and motility are common, and cause either delayed or accelerated transit through the stomach, small intestine or colon, and affect one or more regions. Assessment of regional and/or whole gut transit times can provide direct measurements and diagnostic information to explain the cause of symptoms, and plan therapy. Purpose Recently, several newer diagnostic tools have become available. The American and European Neurogastroenterology and Motility Societies undertook this review to provide guidelines on the indications and optimal methods for the use of transit measurements in clinical practice. This was based on evidence of validation including performance characteristics, clinical significance, and strengths of various techniques. The tests include measurements of: gastric emptying with scintigraphy, wireless motility capsule, and 13 C breath tests; small bowel transit with breath tests, scintigraphy, and wireless motility capsule; and colonic transit with radioopaque markers, wireless motility capsule, and scintigraphy. Based on the evidence, consensus recommendations are provided for each technique and for the evaluations of regional and whole gut transit. In summary, tests of gastrointestinal transit are available and useful in the evaluation of patients with symptoms suggestive of gastrointestinal dysmotility, since they can provide objective diagnosis and a rational approach to patient management.

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“…GI transit can also be assessed through the use of ingestible telemetric capsules, which can record biological properties such as pH from within the lumen of the gut (6,39). Although such technology has existed for over 50 years (12), it is only recently that commercially produced devices have become available and have been promoted for clinical use (6). For pHsensitive devices, fundamental to the validity of such a technique is the knowledge of the precise anatomical location of any pH change.…”

mentioning

confidence: 99%