Obstructive jaundice in a child with pancreatic hemangioma

Hibi, Masahito; Tokiwa, Kaichi; Fukata, Ryoichi; Nakajima, Futoshi

doi:10.1007/s00383-005-1487-5

Cited by 7 publications

(4 citation statements)

References 9 publications

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“…PD was performed with diagnosis of panNET because the boy's parents refused FNA biopsy and insisted on surgery. So far, only 2 cases of obstructive jaundice caused by pancreatic head hemangioma has been reported [14,15] (aged 5 months and 2 years old respectively) and neither of the tumors were removed. According to it, PD or even operation is not the best choice for the boy although his parents were satis ed with his rapid recovery.…”

Section: Discussionmentioning

confidence: 99%

Pancreaticoduodenal and choledochal hemangiomatosis with vascular variation in a child: a rare disease with challenge starts from diagnosis（a case report）

Da-guang

Zhu

Wei

2022

Preprint

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Background Visceral hemangiomatosis is a benign tumor that is rarer than hemangioma and it has not been reported to occur at pancreas, duodenum and choledoch. So it is easy to be confused it with other pancreatic tumors or choledocholithiasis secondary to bile excretion disorder caused by compression of hemangiomatosis. Case presentation We reported a case of a 2 years and 9 months old child presented with repeated and fluctuating jaundice for 3 months following history of endoscopic stone removal with diagnosis of choledocholithiasis in local hospital. Abdominal CT revealed pancreatic head tumor which was undiagnosed before. A rare vascular variation as CMT was also found. Misdiagnosed as pancreatic neuroendocrine tumor, PD was performed. However, history reported pancreaticoduodenal and choledochal hemangiomatosis. Although the boy was in good condition and gained 4Kg in weight 3 months after operation, PD was not the best choice for him if we could make accurate diagnosis before or during operation. Conclusion Our report highlights the difficulty in diagnosing visceral hemangiomatosis and indicates the need for radiologists, endoscopists and surgeons to consider such a possibility when they are confronted with repeated and fluctuating jaundice which can’t be explained by simple choledocholithiasis.

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Section: Discussionmentioning

confidence: 99%

Pancreaticoduodenal and choledochal hemangiomatosis with vascular variation in a child: a rare disease with challenge starts from diagnosis（a case report）

Da-guang

Zhu

Wei

2022

Preprint

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“…Studies have shown that among children with hemangiomatosis treated with corticosteroids, about one-third responded well, whereas one-third gained no benefit [ 5 ]. Although interferon-alpha was administered to severely ill patients, it caused severe side effects [ 14 ]. In recent years, anti-VEGF drugs [ 15 ], such as ranibizumab and bevacizumab, have been used clinically.…”

Section: Discussionmentioning

confidence: 99%

Pancreaticoduodenal and choledochal hemangiomatosis with vascular variation in a child: a rare disease with challenge starts from diagnosis—a case report

2022

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Background Visceral hemangiomatosis is a benign tumor (rarer than hemangioma) that has not been reported to occur in the pancreas, duodenum, or choledoch. It can be easily confused with other pancreatic tumors or choledocholithiasis. Herein, we describe a case of a child with pancreaticoduodenal and choledochal hemangiomatosis and the key characteristics for the accurate diagnosis of pancreatic tumors based on previous reports and our findings. Case presentation We report a case of a 2-year and 9-month-old child who presented with repeated and fluctuating jaundice for 3 months with a history of endoscopic stone removal in a local hospital, following the diagnosis of choledocholithiasis. An abdominal computed tomography revealed a previously undiagnosed pancreatic head tumor and celio-mesenteric trunk (a rare vascular variation). This was misdiagnosed as a pancreatic neuroendocrine tumor. Since the patient’s parents refused FNA biopsy and insisted on surgery, pancreaticoduodenectomy was performed; however, postoperatively, the child was correctly diagnosed with pancreaticoduodenal and choledochal hemangiomatosis. Although the patient was in good condition and had gained 4 kg in weight 3 months postoperatively, pancreaticoduodenectomy could have been avoided if an accurate diagnosis had been established before or during the operation. Conclusion Our report highlights the difficulty in diagnosing visceral hemangiomatosis. Radiologists, endoscopists, and surgeons should consider this possibility in cases of repeated and fluctuating jaundice that cannot be explained by choledocholithiasis alone.

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“…Размеры образований, по данным литературы, варьируют от 30 мм до 20 см [2]. Поскольку чаще гемангиому выявляют в головке поджелудочной железы (66%) [18], она проявляет себя болью [11,14], а также клинической симптоматикой, связанной с механической желтухой [18,20], тошнотой [7,18], возможны желудочнокишечное кровотечение, рвота кровью, мелена [2,7,15,21]. При лабораторном исследовании возможно выявление анемии и тромбоцитопении [7,22].…”

Section: êëèíè÷åñêèå íàáëþäåíèÿunclassified

“…В дальнейшем проводили динамическое наблюдение. Через три года после операции гемангиома поджелудочной железы практически исчезла [20]. Аналогичной тактике при лечении пациента придерживались и другие авторы [9].…”

Section: êëèíè÷åñêèå íàáëþäåíèÿunclassified

Pancreatic Hemangioma

et al. 2018

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Hemangioma is extremely seldom localized in pancreas. In the analysis of PubMed, Scopus and eLibrary databases 53 cases of pancreatic hemangioma have been revealed since 1924. Tumors are predominantly revealed in women aged from 30 till 79 years. All radiological diagnostic methods may be used to diagnose pancreatic hemangioma. Diagnostic criteria don't differ from those in case of other localizations of hemangioma. MRI is the most effective method of pancreatic hemangioma diagnostics because it gives the chance to diagnose neoplasm effectively and also to verify a phase of its development without radiation exposure. Literature review and case report are presented in the article.

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Obstructive jaundice in a child with pancreatic hemangioma

Cited by 7 publications

References 9 publications

Pancreaticoduodenal and choledochal hemangiomatosis with vascular variation in a child: a rare disease with challenge starts from diagnosis（a case report）

Pancreaticoduodenal and choledochal hemangiomatosis with vascular variation in a child: a rare disease with challenge starts from diagnosis（a case report）

Pancreaticoduodenal and choledochal hemangiomatosis with vascular variation in a child: a rare disease with challenge starts from diagnosis—a case report

Pancreatic Hemangioma

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