Obstructive Sleep Apnea as an Independent Stroke Risk Factor

Abstract

OSA is highly prevalent in patients with stroke/TIA independently increasing stroke risk. CPAP studies revealed reduced stroke recurrence and improved recovery with feasible initiation in stroke units. Patients with stroke/TIA have less OSA-associated daytime sleepiness and obesity, making the usual screening tools insufficient and CPAP adherence challenging. Treating OSA decreases stroke prevalence and mortality. OSA initiatives empower neuroscience nurses to integrate this OSA evidence into clinical practice and improve stroke/TIA patient outcomes.

Association Between Obstructive Sleep Apnea-Hypopnea Syndrome and Outcomes in Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease

“…OSAHS patients had an adjusted OR of 1.733 for the MACCE when compared with patients without sleep apnea. Interestingly, we observed that stroke accounted for one-fifth of MACCE in the current study, 16 in patients with OSAHS and 7 in the control group, which is consistent with previous findings indicating OSAHS as an independent risk factor for stroke (13,36,37).…”

Obstructive sleep apnea, COPD, the overlap syndrome, and mortality: results from the 2005–2008 National Health and Nutrition Examination Survey

“… 25 – 31 OSA has been associated with increased chance of a number of serious adverse cardiovascular events that can result in death, such as pulmonary and systemic hypertension, arrhythmia, myocardial ischemia/infarction, stroke, and heart failure. 28 – 30 In addition, chronic kidney disease has been found to be significantly associated with OSA in a large population study of men. 32 Important risk factors for death in patients with COPD include cancer and cardiovascular disease.…”

Sleep-disordered breathing in patients with acute cerebral stroke

“…В противоположность ЦА, ОА, вероятнее всего, является не следствием инсульта, а фактором риска его развития. Несмотря на то, что в настоящем исследовании не было возможности установить факт наличия ОА у пациентов основной группы до начала заболевания, данные литературы свидетельствуют в пользу такого предположения [20].…”