Obstructive Sleep Apnea, Palatal Morphology, and Aortic Dilatation in Marfan Syndrome Growing Subjects: A Retrospective Study

Laganà, Giuseppina; Venza, Nicolò; Malara, Arianna; Liguori, Claudio; Cozza, Paola; Pisano, Calogera

doi:10.3390/ijerph18063045

Cited by 8 publications

(9 citation statements)

References 29 publications

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“…It also shows the parameters that weren't used in other research. In the paper [25] Oxygen Saturation (SpO2) (91.3 ± 2.0) % The oxygen saturation for sleep apnea patient is in this range.…”

Section: Comparative Analysismentioning

confidence: 94%

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Development of an IoT-Based Sleep Apnea Monitoring System for Healthcare Applications

Dhruba

Alam

Khan

et al. 2021

Computational and Mathematical Methods in Medicine

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Sleep is an essential and vital element of a person’s life and health that helps to refresh and recharge the mind and body of a person. The quality of sleep is very important in every person’s lifestyle, removing various diseases. Bad sleep is a big problem for a lot of people for a very long time. People suffering from various diseases are dealing with various sleeping disorders, commonly known as sleep apnea. A lot of people die during sleep because of uneven body changes in the body during sleep. On that note, a system to monitor sleep is very important. Most of the previous systems to monitor sleeping problems cannot deal with the real time sleeping problem, generating data after a certain period of sleep. Real-time monitoring of sleep is the key to detecting sleep apnea. To solve this problem, an Internet of Things- (IoT-) based real-time sleep apnea monitoring system has been developed. It will allow the user to measure different indexes of sleep and will notify them through a mobile application when anything odd occurs. The system contains various sensors to measure the electrocardiogram (ECG), heart rate, pulse rate, skin response, and SpO2 of any person during the entire sleeping period. This research is very useful as it can measure the indexes of sleep without disturbing the person and can also show it in the mobile application simultaneously with the help of a Bluetooth module. The system has been developed in such a way that it can be used by every kind of person. Multiple analog sensors are used with the Arduino UNO to measure different parameters of the sleep factor. The system was examined and tested on different people’s bodies. To analyze and detect sleep apnea in real-time, the system monitors several people during the sleeping period. The results are displayed on the monitor of the Arduino boards and in the mobile application. The analysis of the achieved data can detect sleep apnea in some of the people that the system monitored, and it can also display the reason why sleep apnea happens. This research also analyzes the people who are not in the danger of sleeping problems by the achieved data. This paper will help everyone learn about sleep apnea and will help people detect it and take the necessary steps to prevent it.

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Section: Comparative Analysismentioning

confidence: 94%

“…In the paper [25] Oxygen saturation (SpO2) (91:3 ± 2:0) % The oxygen saturation for sleep apnea patients is in this range In the paper [6] Heart rate (70:9 ± 2:2) bpm The study detected sleep apnea in this range of heart rate. In the paper [26] Polysomonography 91.8% to 96.5% accuracy on adaptive apnea index…”

Section: Referencementioning

confidence: 96%

Development of an IoT-Based Sleep Apnea Monitoring System for Healthcare Applications

Dhruba

Alam

Khan

et al. 2021

Computational and Mathematical Methods in Medicine

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“…Despite all of these, the etiology of OSAS remains controversial. It is now considered a multifactorial disease caused by various factors such as adenotonsillar hypertrophy, allergic rhinitis, obesity, craniofacial anomalies, genetic and/or congenital neuromuscular diseases, cleft palate, a contracted upper jaw or changes in lingual posture [ 4 , 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

The Efficacy of Lingual Laser Frenectomy in Pediatric OSAS: A Randomized Double-Blinded and Controlled Clinical Study

Fioravanti

Zara

Vozza

et al. 2021

IJERPH

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This randomized, double-blind and controlled clinical trial investigates how a diode laser lingual frenectomy can improve obstructive sleep apnea syndrome (OSAS) in pediatric patients. Background: Several authors have shown that a short lingual frenulum causes a reduction in incoming air flow and the relationship between OSAS and a short lingual frenulum. Methods: Thirty-two pediatric patients were equally randomly divided into a Study Group (SG) and a Control Group (CG). On each SG patient a polysomnography 1 (PSG1) and a lingual frenectomy were performed using a diode laser via Doctor Smile Wiser technology, power 7 W. After three months, a new polysomnography (PSG2) was performed to evaluate the lingual frenectomy efficacy in pediatric patients. The pain was assessed by a numerical rating scale (NRS) before and after surgery. The CG followed the same protocol without a lingual frenectomy but myofunctional and speech therapy were conducted to qualitatively and quantitatively improve the lingual functionality. In the SG, eight subjects (50%) had severe OSAS and eight had moderate (50%) while in the CG, three subjects had severe OSAS (18.8%) and thirteen had moderate (81.2%). Results: In the SG, 93.8% were classified as mild OSAS and 6.2% as moderate. In contrast, in the CG, 18.75% were classified as mild OSAS, 62.5% as moderate and 18.75% as severe. Conclusion: The study demonstrates how a lingual laser frenectomy can improve OSAS in pediatric patients.

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“…OSAS has been associated with several systemic disorders, such as hypertension, diabetes, and dyslipidemia. Accordingly, large evidence supports the relation between OSAS and cardiovascular risk [ 3 , 4 , 5 ]. Several mechanisms linking OSAS to its consequences have been identified, and oxidative stress represents one of the main triggering events leading to the increased cardiovascular risk.…”

Section: Introductionmentioning

confidence: 99%

Saliva Analysis of pH and Antioxidant Capacity in Adult Obstructive Sleep Apnea Patients

Venza

Alloisio

Gioia

et al. 2022

IJERPH

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Background: Obstructive sleep apnea syndrome (OSAS) may be associated with and activates the stress response system, and variation in the physiological antioxidant capacity of body fluids. Our aim was to evaluate the variation of pH and antioxidant capacity on the saliva of obstructive sleep apnea subjects (OG) compared to a control group (CG). Method: Fifty subjects with moderate/severe OSAS were recruited in Tor Vergata Hospital and compared with 20 healthy subjects CG. The buffer and the antioxidant capacity of the samples were quantified measuring the pH and the percentage of total salivary antioxidant capacity (%TAC), which refers to the reduced glutathione salivary concentration (GSH). Moreover, the protein concentration and the gelatinolytic activity of metalloproteinases were quantified. Results: The data showed that the pH value is slightly more alkaline in OSAS subjects; however, it is not directly related to the severity of OSAS. The %TAC was found to be significantly reduced by 86.2% in the OG. Proteins of saliva from the OG were found 1.5 times more concentrated than in the healthy sample. The gelatinolytic activity of metalloproteinases of healthy and OSA did not show statistically significant changes. Conclusions: The salivary samples from OSAS compared to CG show an alteration of the oxidative state, the pH buffering power, and protein concentrations, inducing conditions that can easily evolve chronic gingivitis. Further investigations are necessary to evaluate the feasibility of using salivary fluid for the early diagnosis of oral or systemic problems in OSAS subjects.

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Obstructive Sleep Apnea, Palatal Morphology, and Aortic Dilatation in Marfan Syndrome Growing Subjects: A Retrospective Study

Cited by 8 publications

References 29 publications

Development of an IoT-Based Sleep Apnea Monitoring System for Healthcare Applications

Development of an IoT-Based Sleep Apnea Monitoring System for Healthcare Applications

The Efficacy of Lingual Laser Frenectomy in Pediatric OSAS: A Randomized Double-Blinded and Controlled Clinical Study

Saliva Analysis of pH and Antioxidant Capacity in Adult Obstructive Sleep Apnea Patients

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