OC-01 Venous thromboembolism in relation to in vitro fertilization – An approach to determining the incidence and increase in risk in successful cycles

Rova, Karin; Passmark, Henrik; Lindqvist, P.G.

doi:10.1016/s0049-3848(13)70027-6

Cited by 1 publication

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“…В основной группе уровень ФМ был выше в 1,8 раза у пациенток с биохимически подтвержденной беременностью, чем у женщин с отрицательным исходом ЭКО, и в 2,5 раза выше, чем в контрольной группе. Это подтверждает мнение ряда авторов о том, что нарастание прокоагулянтных свойств крови начинается с ранних сроков беременности [20,21].…”

Section: Discussionunclassified

“…Анализ антропометрических показателей не показал значимые различия между группами. ИМТ в основной группе составил 23,5 [21,4] кг/м 2 , в контрольной -22,4 [20,[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]4] кг/м 2 . Несмотря на отсутствие статистически значимой разницы в ИМТ (р = 0,1), ожирение встречалось чаще среди пациенток основной группы, чем контрольной: 14 (38,89%) против 2 (6,25%) соответственно (p = 0,007).…”

Section: результатыunclassified

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Hemostasis in Infertile Patients Participating in Assisted Reproduction Programmes

Godzoeva¹,

Zazerskaya²,

Vlasov³

et al. 2021

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Study Objective: To evaluate the impact of multifollicular ovarian stimulation in in vitro fertilisation (IVF) programmes on hemostasis. Study Design: perspective comparative study. Materials and Methods. The study included 68 patients divided into two groups: study group (n = 36) — infertile patients; control group (n = 32) — healthy non-pregnant women of reproductive age. The protocol with gonadotrophin releasing hormone antagonists was used for ovulation stimulation. Hemostasis system in study patients was evaluated in 2 weeks after embryos were transferred to uterus; in control group — on day 20–22 of menstrual period. For the study group, we evaluated clotting test parameters of hemostasis system, D-dimers (D-d) and fibrin monomer (FM). Study Results. We have not found statistically significant differences between hemostasis screening results of study groups. We have identified increase in pro-coagulatory properties of blood in the study group patients: increase in FM and D-d (р < 0.0001 in both cases). There is an association between study parameters and pregnancy (p < 0.001) and no association with obesity, age and infertility. Conclusion. In IVF programme, FM and D-d levels rise, evidencing hypercoagulation development. An increase in FM levels was even more significant and can be used as an early and specific fibrogenesis marker. Keywords: assisted reproductive technologies, fibrin monomer, D-dimer, hypercoagulation, venous thromboembolic events.

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Section: Discussionunclassified