Occult dysraphism presenting with acro‐osteolysis

Gopinath, Hima; Meghana, Valeti; Karthikeyan, Kaliaperumal

doi:10.1111/pde.13490

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Lastly, unilateral lower extremity acro-osteolysis has been reported as the presenting feature of occult spinal dysraphism in several patients including cases in children [ 51 , 52 ]. Whereas most causes of acro-osteolysis outlined above would manifest with bilateral involvement, unilateral acro-osteolysis should prompt the clinician to consider local trauma and spinal dysraphism in the differential diagnosis.…”

Section: Methodsmentioning

confidence: 99%

Lost bones: differential diagnosis of acro-osteolysis seen by the pediatric rheumatologist

et al. 2021

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Introduction Acro-osteolysis is a radiographic finding which refers to bone resorption of the distal phalanges. Acro-osteolysis is associated with various conditions and its presence should prompt the clinician to search for the underlying etiology. The aim of this review is to discuss disorders with which acro-osteolysis is associated and their distinguishing features, with a focus on the pediatric population. Methods A targeted literature review was performed using the term “acro-osteolysis” in combination with other key terms. The primary search results were supplemented using reference citations. Articles published prior to the year 2000 were included if they described additional associations not encountered in the more recent literature. Results Genetic disorders (particularly primary hypertrophic osteoarthropathy and skeletal dysplasias) and rheumatic diseases (particularly psoriatic arthritis and systemic sclerosis) are the most frequently encountered conditions associated with acro-osteolysis in children. Hyperparathyroidism, neuropathy, local trauma and thermal injury, and spinal dysraphism should also be included in the differential diagnosis. Conclusion Although acro-osteolysis is uncommon, its presence should prompt the clinician to consider a differential diagnosis based on clinical and radiographic features.

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Section: Methodsmentioning

confidence: 99%