Occupational allergic contact dermatitis from ethylhexylzinc dithiophosphate and fatty acid polydiethanolamide in cutting fluids

Occupational allergic contact dermatitis from the extreme pressure (EP) additive zinc, bis ((O,O′‐di‐2‐ethylhexyl) dithiophosphate) in neat oils

“…To date, only 1 article (2) describes a machinist allergic to the EPA zinc, bis ((O,O′‐di‐2‐ethylhexyl) dithiophosphate), a primary dialkyl dithiophosphate, in the aforementioned report. This EPA zinc is also often called 2‐ethylhexyl zinc dithiophosphate (EHZDTP) in material safety data sheets (MSDS).…”

Contact sensitizations in metalworkers with occupational dermatitis exposed to water-based metalworking fluids: results of the research project ?FaSt?

“…Additionally, sensitizations to formaldehyde, benzisothiazolinone (BIT), methylchloroisothazolinone/methylisothazolinone (MCI/MI), colophony, p-phenylenediamine (PPD), p-aminoazobenzene (PAAB), dichromate, and cobalt have been described, although the clinical relevance of these findings could not always be established (Alomar et al 1985;de Boer et al 1989b;Grattan et al 1989, Nethercott et al 1990Uter et al 1993Uter et al , 1996. In case reports of metal workers exposed to wb MWF with occupational contact dermatitis, sensitizations to the following wb MWF components have been reported during the last decade: diglycolamine ), ethylenediamine, possibly as indicator for a sensitization to other amines (Fisher 1998), monoethanolamine (Koch 1995;Owen et al 2000), alkanolaminborates (Bruze et al 1995, a condensate of boric acid, monoethanolamine, and fatty acids (Jensen and Andersen 2003), fatty acid polydiethanolamide (Kanerva et al 2001), oleyl alcohol (Koch 1995), tertiary-butylhydroquinone (Meding 1996), iodopropynyl butylcarbamate (Majoie and van Ginkel 2000), sodium pyrithione (Isaksson 2002;Le Coz 2001), ethylhexylzinc dithiophosphate , Kanerva et al 2001, and oak moss resin (Owen et al 2000).…”

Contact allergy to 2,5‐dimercapto‐1,3,4‐thiadiazole and phenyl‐α‐naphtylamine, allergens in industrial greases and lubricant oils – contact allergy to water‐insoluble greases is uncommon but needs to be considered in some workers

“…We reviewed the test files at FIOH from January 2000 to March 2007 for allergic reactions (+/++/+++) to the following allergens in greases and lubricants: 2,5‐dimercapto‐1,3,4‐thiadiazole (2% in petrolatum, in‐house preparation made from Oloa 4452X, a chemical delivered by the French manufacturer (Chevron Oronite, France) of the guide‐way oil of patient 1, see below), PAN [1% in pet., in‐house preparation (5)], tertiary butyl hydroquinone (1% pet., Chemotechnique, Vellinge, Sweden), EHZDTP [in‐house preparation of 1% Additin 3180 in pet. ; Additin 3180 contains 78% EHZDTP and 22% mineral oil (9)], Coconut diethanolamide (0.5% in pet., Chemotechnique), and Dipentene (1% in pet., Chemotechnique). The patch tests were performed using the Finn Chambers on Scanpore tape (Epitest, Tuusula, Finland).…”