Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit (PREBIS study data)

Abstract

Grande I, Goikolea JM, de Dios C, González‐Pinto A, Montes JM, Saiz‐Ruiz J, Prieto E, Vieta E, for the PREBIS group. Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit PREBIS study data).Objective: Patients diagnosed with bipolar disorder (BD) are reported to have significant work impairment during interepisode intervals. This study was carried out to assess potential predictors of occupational disability in a longitudinal follow‐up of euthymic patients.Method: We included 327 euthymic patients diagnosed with BD type I or type II, 226 of whom were employed and 101 were receiving a severe disablement benefit (SDB). Sociodemographic data were studied and episode recurrence was assessed along a 1‐year follow‐up. Logistic regression analysis was applied to determine predictors of receiving SDB. Cox regression was built to study recurrences.Results: Predictors of receiving SDB were: axis II comorbidity [Odds Ratio (OR) = 2.94, CI: 1.26–6.86, P = 0.013], number of manic episodes (OR = 1.21, CI: 1.10–1.34, P < 0.001), being without stable partner (OR = 2.44, CI: 1.34–4.44, P = 0.004) and older age (OR = 1.08, CI: 1.05–1.12, P < 0.001). Bipolar patients receiving SDB presented more episodic recurrences regardless of polarity than employed bipolar patients (P = 0.002). The time until recurrence in 25% of the bipolar patients receiving SDB was 6.08 months (CI: 4.44–11.77) being 13.08 months (CI: 9.60 to –) in the employed group.Conclusion: Occupational disability in bipolar patients is associated with axis II comorbidity, more previous manic episodes, not having a stable relationship, older age, and more recurrences at 1‐year follow‐up.

Epidemiology and burden of bipolar disorder in Africa: a systematic review of data from Africa

“…In Nigeria, Adegbaju et al [20] found that patients with bipolar disorder though adjudged to be clinically stable had substantial disability. This corroborates reports from outside Africa which indicates that there is the presence of residual functional impairment in patients with bipolar disorder despite resolution of the acute syndromes [4,34,42].…”

Predictors of long‐term work disability among patients with type I and II bipolar disorder: a prospective 18‐month follow‐up study

“…Grande et al. and Schoeyen et al. also found higher age to be associated with receiving a disability pension.…”

“…Grande et al. analyzed the differences between those receiving severe disability benefit and those employed among 327 euthymic Spanish outpatients with BD. They found that predictors of receiving disability pension were Axis II comorbidity, number of manic episodes, being without a stable partner, and older age.…”

A bipolar II cohort (ABC): The association of functional disability with gender and rapid cycling

“…However, the latter two features are also more common in females than males and so a question remains as to whether the association is to a BP sub-type or gender (Kupka et al, 2005). Also, functional levels vary across studies (Grande et al, 2013;Maina et al, 2013;Ruggero et al, 2007;Judd et al, 2003).…”