Occupational exposures and the risk of COPD: dusty trades revisited

Blanc, Paul D.; Iribarren, Carlos; Trupin, Laura; Earnest, Gillian; Katz, Patricia P.; Balmes, John R.; Sidney, Stephen; Eisner, Mark D.

doi:10.1136/thx.2008.099390

Cited by 207 publications

(158 citation statements)

References 37 publications

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“…The studies comprised a total of 92 452 subjects. In some cases, a job-exposure matrix (JEM) was used to characterize the exposure (32)(33)(34)(35), while others use JEM jointly with an expert opinion (35) or a questionnaire (32)(33)(34). Use of record-defined (16 occupational categories) description of exposure was limited (40), while in 20 studies (36-39, 41-56) the exposure was self-reported and questionnaire-based.…”

Section: Population-based Studiesmentioning

confidence: 99%

Occupational chronic obstructive pulmonary disease: a systematic literature review

Omland

Würtz

Aasen³

et al. 2013

Scand J Work Environ Health

121

100

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Occupational chronic obstructive pulmonary disease: a systematic literature review by Omland Ø, Würtz ET, Aasen TB, Blanc P, Brisman J, Miller MR, Pedersen OF, Schlünssen V, Sigsgaard T, Ulrik CS, Viskum S This review on occupational chronic obstructive pulmonary disease (COPD) addresses some of the potential limitations of earlier assessments by restricting the studies included to high quality epidemiological analysis involving only spirometrically confirmed air-flow obstruction as the outcome. The authors combined this with minimal requirements for exposure characterization allowing for analysis of population-based studies. Affiliation 19Review Scand J Work Environ Health. 2014;40(1):19-35. doi:10.5271/sjweh.3400 Occupational chronic obstructive pulmonary disease: a systematic literature review Objective Occupational-attributable chronic obstructive pulmonary disease (COPD) presents a substantial health challenge. Focusing on spirometric criteria for airflow obstruction, this review of occupational COPD includes both population-wide and industry-specific exposures.Methods We used PubMed and Embase to identify relevant original epidemiological peer-reviewed articles, supplemented with citations identified from references in key review articles. This yielded 4528 citations. Articles were excluded for lack of lung function measurement, insufficient occupational exposure classification, lack of either external or internal referents, non-accounting of age or smoking effect, or major analytic inadequacies preventing interpretation of findings. A structured data extraction sheet was used for the remaining 147 articles. Final inclusion was based on a positive qualitative Scottish Intercollegiate Guidelines Network (SIGN) score (≥2+) for study quality, yielding 25 population-wide and 34 industry/occupation-specific studies, 15 on inorganic and 19 on organic dust exposure, respectively. ResultsThere was a consistent and predominantly significant association between occupational exposures and COPD in 22 of 25 population-based studies, 12 of 15 studies with an inorganic/mineral dust exposure, and 17 of 19 studies on organic exposure, even though the studies varied in design, populations, and the use of measures of exposure and outcome. A nearly uniform pattern of a dose-response relationship between various exposures and COPD was found, adding to the evidence that occupational exposures from vapors, gas, dust, and fumes are risk factors for COPD. ConclusionThere is strong and consistent evidence to support a causal association between multiple categories of occupational exposure and COPD, both within and across industry groups.Key terms: airflow obstruction; COPD; dust; fume; gas; lung function measurement; occupational exposure; vapor. Chronic obstructive pulmonary disease (COPD) represents serious morbidity and has emerged as a leading cause of death worldwide (1). Although tobacco smoking is the leading factor in the etiology of COPD, the disease may be caused by inhalation of different gases and aerosols among bot...

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Section: Population-based Studiesmentioning

confidence: 99%

Occupational chronic obstructive pulmonary disease: a systematic literature review

Omland

Würtz

Aasen³

et al. 2013

Scand J Work Environ Health

121

100

View full text Add to dashboard Cite

show abstract

“…4,5 The heterogeneity of COPD may be due to the variations in genetic influences and environmental exposures among which exposures to biomass fuels and dusty jobs were reported to be related with the development of COPD in Asia. 6,7 Therefore, to assess the heterogeneity of COPD, it would be reasonable to compare the exposure history of biomass fuels and dusty jobs, demographic characteristics, and clinical characteristics of COPD patients from different cities or regions.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of stable chronic obstructive pulmonary disease patients in the pulmonology clinics of seven Asian cities

Oh¹,

Bhome²,

Boonsawat³

et al. 2013

COPD

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Background and objectives: Chronic obstructive pulmonary disease (COPD) is responsible for significant morbidity and mortality worldwide. We evaluated the characteristics of stable COPD patients in the pulmonology clinics of seven Asian cities and also evaluated whether the exposure to biomass fuels and dusty jobs were related to respiratory symptoms, airflow limitation, and quality of life in the COPD patients. Methods: This cross-sectional observational study recruited 922 COPD patients from seven cities of Asia. The patients underwent spirometry and were administered questionnaires about their exposure to cigarette smoking, biomass fuels, and dusty jobs in addition to respiratory symptoms and health related quality of life. Results: Of the patients, there appeared to be variations from city to city in the history of exposure to biomass fuels and dusty jobs and also in respiratory symptoms of cough, phlegm, wheeze, and dyspnea. These symptoms were more frequent in those COPD patients with a history of exposure to biomass fuels than without and those with a history of exposure to dusty jobs than without (P , 0.01 for all comparisons). Airflow limitation was more severe in those COPD patients with a history of exposure to biomass fuels than without (52.2% predicted versus 55.9% of post-bronchodilator forced expiratory volume in 1 second [FEV 1 ], P = 0.009); quality of life was poorer in those with exposure to biomass fuels than without (40.4 versus 36.2 of the St George's Respiratory Questionnaire [SGRQ] total score, P = 0.001). Airflow limitation was more severe in those COPD patients with a history of exposure to dusty jobs than without (51.2% predicted versus 57.3% of post-bronchodilator FEV 1 , P , 0.001); quality of life was poorer in those with dusty jobs than without (41.0 versus 34.6 of SGRQ score, P = 0.006). Conclusion: In Asian cities, the characteristics of COPD patients vary and the history of exposure to biomass fuels or dusty jobs was related to frequency of symptoms, severe airflow limitation, and poor quality of life.

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“…Existen estudios (Balmes et al, 2003;Govender, Lalloo y Naidoo, 2011;Hnizdo, Sullivan, Bang y Warner, 2002) que avalan el efecto de la exposición profesional entre trabajadores de muy diversas ocupaciones (industrias plásticas, textiles, manufactura de productos alimentarios, construcción, agricultura, limpieza profesional) y que la asociación de esta exposición con el tabaquismo aumenta aún más el riesgo de desarrollar EPOC (Blanc et al, 2009).…”

Section: Discussionunclassified

Cómo vivir con EPOC: percepción de los pacientes.

Muñoz-Cobos

Guasch²,

Cuenca-del-Moral

et al. 2015

AN PSICOL-SPAIN

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The aim of this study is to determine the mental model that patients with COPD (chronic obstructive pulmonary disease<strong>)</strong>have about their illness analyzed by the Leventhal´s Common Sense of Self-Regulation Model. An exploratory-descriptive study using qualitative methodology was performed. We included COPD-diagnosed patients attending three urban and a rural primary care centres. We used video-taped group interviews and transcribed them using Atlas.Ti 5.2 program. 22 group interviews (2009 - 2011) and 58 patients were included. There were 3 additional sessions to final inform validation. The results show that patients did not have a defined mental model about COPD: this disease was insufficiently recognized; diagnosis was made in exacerbations and it was confused with other diseases; the cause of illness was related to tobacco consumption and to “something else”: fumes, colds and hard work. Patients tended to minimize their symptoms and limitations. Participants had wrong beliefs about colds, smoking only a few cigarettes effects and damage of inhaled treatment. Emotions as despair, resignation and fear were reported. We conclude that COPD patients showed confusion about many aspects of the disease (causes, symptoms, treatments). It was difficult to identify a mental model of the disease among COPD patients. <p> </p>

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Occupational exposures and the risk of COPD: dusty trades revisited

Cited by 207 publications

References 37 publications

Occupational chronic obstructive pulmonary disease: a systematic literature review

Occupational chronic obstructive pulmonary disease: a systematic literature review

Characteristics of stable chronic obstructive pulmonary disease patients in the pulmonology clinics of seven Asian cities

Cómo vivir con EPOC: percepción de los pacientes.

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