Ochromobactrum intermedium: an emerging opportunistic pathogen—case of recurrent bacteraemia associated with infective endocarditis in a haemodialysis patient

Abstract

We describe the first clinical case report of infective endocarditis related to Ochrobactrum intermedium infection. The case involved a 23-year-old man receiving dialysis via an internal jugular long-term haemodialysis catheter. He improved with a prolonged course of meropenem and minocycline. Ochrobactrum spp. are recognized as rare emerging opportunistic pathogens.

The occurrence of Salmonella, extended‐spectrum β‐lactamase producing Escherichia coli and carbapenem resistant non‐fermenting Gram‐negative bacteria in a backyard poultry flock environment

“…While some of these bacteria have been previously isolated from environmental sources, to the best of our knowledge, this is the first report of isolation of B. trematum from backyard poultry environment. Ochrobactrum intermedium has been frequently isolated from cold-and warm-blooded animals including poultry (Alonso, Kwabugge, Anyanwu, Torres, & Chah, 2017;Aujoulat et al, 2014;Bharucha, Sharma, Sharma, Kandil, & Collier, 2016;Sharma et al, 2018). Similarly, H. alvei has been previously isolated from variety of poultry sources including laying hens, pullets, broiler cecal contents, poultry meat products, air samples collected from poultry processing plants, and from rats and lizards cohabitating with poultry (Ajayi, Ogunleye, Happi, & Okunlade, 2015;Hinton, Buhr, & Ingram, 2000;Jemilehin, Ogunleye, Okunlade, & Ajuwape, 2016;Jones, Savell, Acuff, & Vanderzant, 1988;Lenhart, Olenchock, & Cole, 2009;Real et al, 1997;Vazquez-Moreno et al, 2006).…”

Fluoroquinolone resistance of Staphylococcus epidermidis isolated from healthy conjunctiva and analysis of their mutations in quinolone-resistance determining region

“…In other words, in previous domestic studies [5][6][7], it was thought that it was di cult to identify this strain because bacteria were mainly identi ed using biochemical methods. Ochrobactrum intermedium has been reported to cause endophthalmitis in relation to metal ocular foreign bodies [30], and infections other than the eye are rare, so there have not been many studies [29]. It is noteworthy that, despite the strains that were not mentioned at all as constitutive gram-negative bacteria in the previous conjunctival normal ora study in Korea, they were the third most cultivated in this study after S. epidermidis and C. macginley.…”

“…Eguchi et al reported high resistance to cipro oxacin, nor oxacin, and levo oxacin in all 12 of the 16 strains of C. macginley identi ed in specimens from patients with normal conjunctivitis or conjunctivitis before surgery, and reported quinolone-resistant Corynebacterium spp. [29]. Considering this in connection with the decrease in the culture rate of S. epidermidis, the relative increase in Corynebacterium spp.…”

Fluoroquinolone resistance of Staphylococcus epidermidis isolated from healthy conjunctiva and analysis of their mutations in quinolone-resistance determining region

“…In other words, in previous domestic studies [5][6][7], it was thought that it was di cult to identify this strain because bacteria were mainly identi ed using biochemical methods. Ochrobactrum intermedium has been reported to cause endophthalmitis in relation to metal ocular foreign bodies [31], and infections other than the eye are rare, so there have not been many studies [30]. It is noteworthy that, despite the strains that were not mentioned at all as constitutive gram-negative bacteria in the previous conjunctival normal ora study in Korea, they were the third most cultivated in this study after S. epidermidis and C. macginleyi.…”