Ocular adverse reactions to systemic medication

Ocdjhular adverse reactions to tamoxifen—a review

“…It should be stressed that the optometrist must still inform the patient's medical practitioner of the findings that prompted the report, even though an MCA report card has been submitted. There have been three reports by optometrists, to the recently discontinued College of Optometrists' OAR reporting scheme, of macular changes in patients taking tamoxifen (Edgar and Gilmartin, 1997). To screen adequately for early ocular manifestations of tamoxifen toxicity, assessment of visual function should include visual acuities and Amsler grid central field analysis.…”

“…However, the cornea and lens, which are avascular, also commonly exhibit ocular adverse reactions. Many factors may influence whether a patient will suffer an ocular reaction to a systemic drug, including: drug dose and duration, interaction with other systemic drugs, the patient's age and general health (Edgar and Gilmartin, 1997).…”

Assessment of patients with age‐related cataract

“…These opacities can also present earlier than the other morphological types, at about age 55 years. PSC cataracts can be associated with other ocular and systemic disease, such as retinitis pigmentosa and diabetes (Eshagian, 1982) and are found as a side effect of systemic drugs such as oral corticosteroids (Edgar and Gilmartin, 1997).…”

Drug‐induced ocular side‐effects with isotretinoin

“…The role of the UK optometrist in detecting and reporting ocular adverse reactions to systemic medication was established over 30 years ago (Gilmartin, 1987, 2008) and has developed substantially in recent years (Edgar and Gilmartin, 1997; Lawrenson, 2001; Cox and Gilmartin, 2006). Although the professional optometric literature regularly reviews drug‐induced adverse ocular side‐effects of interest to the practicing optometrist (e.g.…”