Of dreaming on solid grounds and silent triumphs of one man: A story about Josef Warkany

Wertelecki, Wladimir

doi:10.1002/ajmg.1320330424

Cited by 5 publications

(2 citation statements)

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“…One of the pioneers of study of teratology (literarily, the study of monsters) was the pediatrician Joseph Warkany 47,48 . Born and educated in Vienna, Warkany moved in 1932 to Children's Hospital in Cincinnati, Ohio, where he worked for the rest of his life.…”

Section: Abnormal Development and Abnormal Genesmentioning

confidence: 99%

How diseases became “genetic”

Löwy

2019

Ciênc. saúde coletiva

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This article examines the origins of the term “genetic disease.” In the late 19 and early 20th century, an earlier idea that diseases that occur in families reflect a vague familiar “predisposition” was replaced by the view that such diseases have specific causes, while Mendelian genetics provided then clues to the patterns of their transmission. The genetictisation of inborn pathologies took a decisive turn with the redefinition, in 1959, of Down syndrome as a chromosomal anomaly, then the development of tests for the diagnosis of other hereditary pathologies. At that time, geneticists distinguished “hereditary” diseases that run in families, from “genetic” conditions that are the result of new mutations during the production of egg and sperm cells. In the latter case, the inborn impairment is produced by an anomaly in the genetic material of the cell, but is not hereditary, because it is not transmitted from one or both parents. In the late 20th and early 21st century, new genomic technologies blurred the distinction between hereditary and genetic impairments, extended the concept of genetic disease, and modified the experience of people living with such a disease.

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Section: Abnormal Development and Abnormal Genesmentioning

confidence: 99%

How diseases became “genetic”

Löwy

2019

Ciênc. saúde coletiva

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“…This year was marked by the passing of Dr. Josef Warkany-viewed as one of the fathers of modern teratology and one of the three founders of the Teratology Society (Brent, 1982;Wertelecki, 1989;Kalter, 1993;Cohen, 1994;Miller, 1995).…”

Section: To 1992mentioning

confidence: 99%

An updated history of the Teratology Society

Shepard

Barr

Brent

et al. 2010

Birth Defects Research

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BACKGROUND: The 49‐year history of the Teratology Society is reviewed. An abbreviated history is outlined in table form, with listings of the Warkany Lectures, the Continuing Education Courses, and officers of the society. The original article was updated to include the years 2000 to 2010. METHODS: A year‐by‐year description of the events is given, including the scientific and social content of the annual meetings and changes in the business of the society, in many cases using comments from the past presidents. The valuable and unique diversity of the members is discussed and illustrated, presenting the disciplines and main research areas of the presidents. The number of submitted abstracts and the various categories are tabulated, averaging the number and type over successive periods. A significant increase in the number of abstracts dealing with epidemiology and developmental biology is evident. The society's development is compared to that of a human, and the question was asked by Shephard et al. (2000): Have we reached the maturational stage of old age or senescence, or is the society still maturing gracefully? This question needs further discussion by all the members. By 2010, many positive changes are happening to revitalize the society. RESULTS: During the past 50 years, we have developed the scientific basis to prevent birth defects caused by rubella, alcoholism, and folate deficiency, as well as other prenatal exposures. We are now taking advantage of advances in many fields to begin shaping the Teratology Society of the 21st century. CONCLUSIONS: We must now engage in political battles to obtain the resources needed to conduct further research and to implement prevention programs, as well as to provide care and rehabilitation for persons with birth defects. Birth Defects Research (Part A), 2010. © 2010 Wiley‐Liss, Inc.

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Josef Warkany's gestation of the teratology society

Wertelecki

2020

Birth Defects Research

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Of dreaming on solid grounds and silent triumphs of one man: A story about Josef Warkany

Cited by 5 publications

References 20 publications

How diseases became “genetic”

How diseases became “genetic”

An updated history of the Teratology Society

Josef Warkany's gestation of the teratology society

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