Older patients with persistent postural-perceptual dizziness exhibit fewer emotional disorders and lower vertigo scores

Abstract

The clinical characteristics of persistent postural-perceptual dizziness (PPPD) vary according to patient age and inducing factors. We aimed to analyze the differences in the clinical characteristics of PPPD with different patient age groups and different etiologies. A total of 122 PPPD patients hospitalized in the vertigo ward of Nanjing Brain Hospital from December 2018 to July 2021 were enrolled. According to whether dizziness symptoms were secondary to organic diseases, PPPD patients were divided into the primary (p-) and secondary (s-) PPPD groups; subgroups were created according to age including youth group, middle-aged group, older adults group 1 and older adults 2. We collected detailed data from each patients, including scores on the Dizziness Handicap Inventory (DHI), mental state and other clinical data. The ratio of males to females was 1:2. The prevalence of emotional disorders in the middle-aged group was the highest (67.57%) and that in the older adults groups was lower (48.08% in older adults group 1 and 8.70% in older adults group 2, P = 0.000). The proportion of p-PPPD patients with emotional disorders was significantly higher than that of s-PPPD patients (53.48% vs. 30.56%, P = 0.028). The average total DHI score in the middle-aged group was significantly higher than that in older adults group 2 (52.86 vs. 35.04, P = 0.032), and the Beck anxiety score in the middle-aged group was higher than that in older adults group 2 (38.89 vs. 27.65, P = 0.000). The middle-aged group had the highest proportion of women, the highest proportion of patients with emotional disorders and the highest vertigo score. The proportion of patients with emotional disorders and the vertigo scores were lower in the older adults groups.

Clinical characteristics of persistent postural‐perceptual dizziness and its visual subtype in Korean patients: A multicenter cross‐sectional study

“…This study examined the sociodemographic and clinical characteristics of Korean patients with PPPD, including variants that did not meet all exaggerating criteria, which had not been previously investigated (Das et al., 2023 ; Popkirov, Staab, et al., 2018 ; Staab, 2020 ). The participants had an average age in the mid‐50s, and the majority were female, consistent with recent research (Adamec et al., 2020 ; Bittar & Lins, 2015 ; Sarna et al., 2021 ; Trinidade & Goebel, 2018 ; Wang et al., 2021 ; Waterston et al., 2021 ; Yan et al., 2017 ; Zhang et al., 2022 ). The higher prevalence of PPPD in women may be attributed to their increased likelihood of experiencing certain vestibular disorders such as vestibular migraine or BPPV (Becker‐Bense et al., 2019 ; Neuhauser, 2016 ; Yetiser & Ince, 2015 ), as well as their increased likelihood of functional neurological disorders (Häuser et al., 2013 ).…”

“…The patient health questionnaire‐9 (PHQ‐9) is a self‐report instrument commonly used to screen for depression. It includes nine questions that evaluate the frequency and intensity of symptoms experienced in the past 2 weeks, and each question is rated on a 0–3 scale (Han et al., 2008 ; Huang et al., 2006 ; Zhang et al., 2022 ).…”

Clinical features of persistent postural-perceptual dizziness with isolated otolith dysfunction as revealed by VEMP and vHIT findings

“…PPPD is often preceded by a peripheral or central vestibular disorder. Benign paroxysmal positional vertigo (BPPV), vestibular migraine, and vestibular neuritis have been reported as background disorders in PPPD ( 2 , 4 , 5 ). Among prolonged deficits due to preceding vestibular disorders, isolated otolith dysfunction could be a potent factor in the development of PPPD, as it has been reported to be present in 20–46% of PPPD patients ( 4 , 6 , 7 ).…”

Comorbid disorders and therapy of persistent postural perceptual dizziness

“…В патогенезе ПППГ ведущую роль играет нарушение адаптации мозга к вестибулярному дефициту с увеличением зависимости от визуальной информации о самодвижении [8][9][10][11][12][13][14]. Причиной рассогласования, лежащего в основе ПППГ, может быть постоянный тревожный контроль за собственной постуральной устойчивостью из-за страха перед возможным падением.…”