Omega-3 supplementation to prevent recurrent preterm birth: a systematic review and metaanalysis of randomized controlled trials

Omega‐3 supplementation during pregnancy to prevent recurrent intrauterine growth restriction: systematic review and meta‐analysis of randomized controlled trials

“…Although non‐significant, there were five perinatal deaths in the placebo group and three in the supplementation group (non‐significant 40% reduction). Our results compare with prior Level 1 data that showed omega‐3 supplementation to be associated with some prolongation of pregnancy.…”

“…Four other meta‐analyses have evaluated the efficacy of omega‐3 supplementation during pregnancy. The first showed that omega‐3 supplementation may increase pregnancy duration and head circumference in low‐risk singleton pregnancies, but the mean effect size was small.…”

Cervical Pessary for Preventing Preterm Birth in Singleton Pregnancies With Short Cervical Length: A Systematic Review and Meta‐analysis

“…Different strategies have been adopted for prevention of SPTB, [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] including progesterone 16,22 and cerclage, 17,18 as well as lifestyle modification such as smoking cessation, 23 diet and aerobic exercise, 24 and nutritional supplements, [25][26][27][28][29][30] including omega-3, 25-28 folic acid, 29 and vitamins. 30 The evidence supports the use of vaginal progesterone in singleton pregnancies with short cervix, 16 while cervical cerclage seems to be beneficial only in the subgroup of women with both prior SPTB and TVU CL 25 mm.…”

“…Different strategies have been adopted for prevention of SPTB, including progesterone and cerclage, as well as lifestyle modification such as smoking cessation, diet and aerobic exercise, and nutritional supplements, including omega‐3, folic acid, and vitamins …”

Cerclage for sonographic short cervix in singleton gestations without prior spontaneous preterm birth: systematic review and meta‐analysis of randomized controlled trials using individual patient‐level data

“…Different strategies have been adopted for preventing PTB, including use of progesterone, cerclage and cervical pessary, as well as lifestyle modification, such as smoking cessation, diet, aerobic exercise and nutritional supplements. The evidence supports the use of vaginal progesterone in singleton pregnancies with short cervix, while cervical cerclage seems to be beneficial only in the subgroup of singleton gestations with both prior spontaneous PTB and CL ≤ 25 mm 10 , but not in singletons without prior PTB or in multiple gestations.…”