On a Numerical Model of a Circadian Oscillator

We consider one system of partial derivative equations of the parabolic type as a model of a simple 3D gene network in the presence of diffusion of its three components. Using discretization of the phase portrait of this system, comparison theorems, and other methods of the qualitative theory of differential equations, we show uniqueness of the equilibrium solution to this system and find conditions of instability of this equilibrium. Then, we obtain sufficient conditions of existence of at least one oscillating functioning regime of this gene network. An estimate of lower and upper bounds for periods of these oscillations is given as well. In quite a similar way, these results on the existence of cycles in 3D gene networks can be extended to higher-dimensional systems of parabolic or other evolution equations in order to construct mathematical models of more complicated molecular–genetic systems.

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On Oscillations in a Gene Network with Diffusion

Golubyatnikov

Ayupova

Kirillova

2023

Mathematics

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On a Numerical Model of a Circadian Oscillator

Cited by 1 publication

References 19 publications

On Oscillations in a Gene Network with Diffusion

On Oscillations in a Gene Network with Diffusion

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