This paper investigates a chemically reactive Magnetohydrodynamics fluid flow with heat and mass transfer over a permeable surface taking into consideration the buoyancy force, injection/suction, heat source/sink and thermal radiation. The governing momentum, energy and concentration balance equations are transformed into a set of ordinary differential equations by method of similarity transformation and solved numerically by Runge- Kutta method based on Shooting technique. The influence of various pertinent parameters on the velocity, temperature, concentration fields are discussed graphically. Comparison of this work with previously published works on special cases of the problem was carried out and the results are in excellent agreement. Results also show that the thermo physical parameters in the momentum boundary layer equations increase the skin friction coefficient but decrease the momentum boundary layer. Fluid suction/injection and Prandtl number increase the rate of heat transfer. The order of chemical reaction is quite significant and there is a faster rate of mass transfer when the reaction rate and Schmidt number are increased.