On Intrauterine Growth

Kloosterman, G.J.

doi:10.1002/j.1879-3479.1970.tb00313.x

Cited by 614 publications

(183 citation statements)

References 8 publications

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“…Birthweight was expressed as a percentage of the Dutch population mean, corrected for sex and gestational age, and as a weight centile [30]. Maternal BMI before the second pregnancy, maternal age at birth of the second child, and time elapsed between the first and second births were calculated from the data in the records.…”

Section: Methodsmentioning

confidence: 99%

Sibling birthweight as a predictor of macrosomia in women with type 1 diabetes

2005

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Aims/hypothesis: The aim of this study was to establish the value of maternal HbA 1 c levels and older sibling birthweight as predictors of birthweight and macrosomia in the offspring of women with type 1 diabetes. Subjects and methods: A total of 214 pregnancies of 107 women with type 1 diabetes were studied. Regression analysis was performed to test the predictive value of the birthweight of the first-born infant, HbA 1 c levels, maternal BMI, maternal age and time between subsequent births on the birthweight of the second-born infant. Birthweights were corrected for sex and gestational age. The percentages of first-and second-born infants with macrosomia (weight >90th centile) were calculated and compared. Results: Only the birthweight of earlier born infants was significantly related to that of second-born infants (p<0.001) and 40-50% of the variation in the birthweight of second-born infants could be explained by the birthweight of the firstborn infants. About 85% of the mothers who gave birth to a macrosomic infant had a macrosomic infant in a subsequent pregnancy. Conclusions/interpretation: Although it is clear that glycaemic control contributes to birthweight in women with type 1 diabetes, the birthweight of an earlier born infant appears to be a much better predictor of the birthweight of a subsequent infant than HbA 1 c levels during pregnancy. It may, therefore, be used to identify patients at risk of giving birth to a macrosomic infant. Daily home monitoring of glucose levels, rather than HbA 1 c levels, should be used for assessment of maternal glycaemia during pregnancy.

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Section: Methodsmentioning

confidence: 99%

Sibling birthweight as a predictor of macrosomia in women with type 1 diabetes

2005

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“…We defined the birthweight ratio as the quotient of the actual birthweight of the infant and the expected birthweight on the 50th percentile of the Dutch intrauterine growth curve for singleton pregnancies corrected for gestational age, sex and parity [13]. All twin placentae were macroscopically and histologically examined, but investigations to establish zygosity such as blood group determination or HLA tissue typing were not routinely done.…”

Section: Methodsmentioning

confidence: 99%

Hypertensive disorders in twin pregnancy

Santema¹,

Koppelaar²,

Wallenburg³

1995

European Journal of Obstetrics & Gynecology and Reproductiv

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Objective: To compare the incidence and severity of pregnancy-induced hypertensive disorders in twin pregnancy and in singleton gestation. Study design: Case-control study in the setting of a University HOspital. Each pregnancy of a consecutive series of 187 twin pregnancies attending the antenatal clinic and booked before a gestational age of 24 weeks was matched for maternal age, parity, and gestational age at delivery with a singleton pregnancy delivered in the same year. Primary end points of the analysis of the course and outcome of pregnancy were pregnancy-induced hypertension and proteinuric pre-eclampsia. Results: In the twin pregnancy group, 21% of patients met the criteria for the diagnosis of a pregnancy-induced hypertensive disorder, compared with 13% in the singleton pregnancy group (P < 0.05). The difference was due to a significantly higher incidence of pregnancy-induced hypertension in twin (15%) than in singleton (6%) pregnancy (P < 0.05), in particular in nulliparous women. The incidence of preeclampsia was similar in twin (6%) and singleton pregnancies (6.5%), without a difference in severity and in the occurrence of the HELLP syndrome. Conclusion: The incidence of non-proteinuric pregnancy-induced hypertension, but not of proteinuric preeclampsia, is increased in twin pregnancy.

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“…Maternal age ranged between 16 and 43 years (median 28 years). All pregnancies were uncomplicated and resulted in a term delivery of normal infants with a birth weight between the 10th and 90th centiles, corrected for maternal parity and fetal sex 9 . Women were selected according to five gestational age subgroups (10-11 weeks, n = 12; 12-13 weeks, n = 12; 14-15 weeks, n = 12; 16-17 weeks, n = 10; 18-19 weeks, n = 9) to guarantee a homogeneous distribution.…”

Section: Subjectsmentioning

confidence: 99%

Assessment of fetal heart rate variability and velocity variability by Doppler velocimetry of the descending aorta at 10–20 weeks of gestation

Ursem

Clark

Keller

et al. 1999

Ultrasound in Obstet & Gyne

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Results From 10 to 20 weeks of gestation, the descending aorta peak systolic and time-averaged velocities increased, whereas the fetal heart rate decreased. The descending aorta peak systolic variability also increased. However, the time-averaged velocity variability and fetal heart rate variability remained constant during the study period. In the subset of 24 women, the fetal heart rate variability and velocity variability data from the descending aorta and umbilical artery were not significantly different.Conclusions Reproducible fetal heart rate and velocity variability data can be derived from the descending aorta and umbilical artery. The increase in heart rate variability observed in the umbilical artery was not seen in recordings obtained from the descending aorta. Different fetal activity states may be the underlying mechanism for these heart rate variability discrepancies.

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On Intrauterine Growth

Cited by 614 publications

References 8 publications

Sibling birthweight as a predictor of macrosomia in women with type 1 diabetes

Sibling birthweight as a predictor of macrosomia in women with type 1 diabetes

Hypertensive disorders in twin pregnancy

Assessment of fetal heart rate variability and velocity variability by Doppler velocimetry of the descending aorta at 10–20 weeks of gestation

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