On Problems of the Comprehensive Chemical Profiling of Medicinal Plants

Морозов, С. В.; Tkacheva, N. I.; Ткачев, А.В.

doi:10.1134/s1068162019070070

Cited by 4 publications

(5 citation statements)

References 83 publications

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“… 12 , 13 At present, at least 80% of the world population use herbal remedies. 13 − 15 Therefore, the studies on the elemental chemical composition of medicinal plants (herbal medicines, i.e., herbal remedies) are currently of particular relevance due to the continuously detected side effects of modern synthetic medicines and the lack of drugs for treating chronic and long-term diseases. However, reduced efficacy, as well as the side effects (deleterious) of herbal remedies, is possible, which is associated with the poor quality of medicinal raw materials and final products.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…However, reduced efficacy, as well as the side effects (deleterious) of herbal remedies, is possible, which is associated with the poor quality of medicinal raw materials and final products. 16 The problem of medicinal raw material contamination with inorganic contaminants is known to be of an apparent regional character and is especially relevant for the regions of medicinal raw material procurement. 19−21 Large industrial enterprises in the region increase the chances of collecting raw materials contaminated with HMs.…”

Section: Introductionmentioning

confidence: 99%

“…The interest in herbal medicine has sharply increased all over the world in recent decades due to its complex of relatively simple technologies to prevent and treat diseases using medicinal plants. , At present, at least 80% of the world population use herbal remedies. − Therefore, the studies on the elemental chemical composition of medicinal plants (herbal medicines, i.e., herbal remedies) are currently of particular relevance due to the continuously detected side effects of modern synthetic medicines and the lack of drugs for treating chronic and long-term diseases. However, reduced efficacy, as well as the side effects (deleterious) of herbal remedies, is possible, which is associated with the poor quality of medicinal raw materials and final products …”

Section: Introductionmentioning

confidence: 99%

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Comparison of Heavy Metal Content in Artemisia austriaca in Various Impact Zones

et al. 2020

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A study on Artemisia austriaca of two anthropogenically heavy metal-polluted impact zones of the Rostov region, namely Lake Atamanskoye and Novocherkasskaya Power Station, was conducted. The influence of soil pollution on the Pb, Zn, and Cu accumulation in various organs of A. austriaca , which is widespread in the studied territories, was established. An extremely high level of Zn content (3051 mg/kg) was observed in the soils of the impact zone of Lake Atamanskoe, as well as an excess over the maximum permissible level for Pb and Cu (32 and 132 mg/kg accordingly). The distribution coefficient (DC) of heavy metal translocation showed the highest mobility of Zn (DC ≥ 1 in 9 out of 11 sites) and the smallest of Pb (DC ≥ 1 in 4 out of 11 sites) in plants of the Novocherkasskaya Power Station impact zone. The zone of increased pollution around Lake Atamanskoye was 1.5 km, which was much smaller than the Novocherkasskaya Power Station zone of high pollution (5 km). However, vehicle emissions accumulated in the soil over the past decades had a greater effect on the Pb translocation than atmospheric emissions of the enterprise.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparison of Heavy Metal Content in Artemisia austriaca in Various Impact Zones

et al. 2020

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“…Over the last 15-20 years qualitative changes have occurred in terms of studying the chemical composition of medicinal plants and crude herbal drug, which is explained by the development of modern spectral and physicochemical methods of analysis. [3][4][5] Nine different taxonomic classifications have been reported for the genus Cyclamen over the last 85 years. The genus Cyclamen is traditionally classified into the Primulaceae family.…”

Section: Introductionmentioning

confidence: 99%

Pharmacognostic, Phytochemical and Ethnopharmacological Potential of Cyclamen coum Mill

Mk¹,

Ev²,

Nv³

et al. 2020

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Background: This review focuses on characterization of Cyclamen coum Mill. (Myrsinaceae), composition and content of biologically active substances presented in the above-ground and underground parts, reporting use of this plant in traditional medicine, predicting possible pharmacotherapeutic effects. Materials and Methods: Various electronic search engines such as Google, Google scholar, scientific literature, electronic databases such as e-Library, Scopus, Web of Science, Pubmed had been searched and data obtained. Results: Cyclamen L. is classified in the Myrsinaceae family now. It is a typical element of the Mediterranean flora. C. coum. is a species characteristic of the Caucasus and Crimea with rounded leaves and rounded corolla lobes, bright and pink-purple flowers. Chemical composition of biologically active substances of C. coum was described in sufficient detail. C. coum contains saponins (coumoside A, coumoside B, cyclaminorin, deglucocyclamin, cyclacoumin, and mirabilin lactone), sterols (stigmasterol and other related compounds), piperidine alkaloid (2-β-D-glycopyranosyl-2-undecil-3,5-dihydroxy-6-carboxypiperidine), flavonoids, phenols, tannins, cardiac glycosides. Antioxidant, antibacterial, antifungal, and antitumor activities are established for different C. coum extracts. Conclusion: C. coum can be used for the production of potential anticancer, antibacterial and antifungal drugs. It should be noted that more pharmacognostic, pharmacological studies are needed for providing further information to use this medicinal plant in the official medicine. Also, standardization procedures for a crude herbal drug should be developed.

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Virtual Screening of Antimicrobial Agents from Medicinal Plants

Zhao

Cheng

2021

Russ J Bioorg Chem

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On Problems of the Comprehensive Chemical Profiling of Medicinal Plants

Cited by 4 publications

References 83 publications

Comparison of Heavy Metal Content in Artemisia austriaca in Various Impact Zones

Comparison of Heavy Metal Content in Artemisia austriaca in Various Impact Zones

Pharmacognostic, Phytochemical and Ethnopharmacological Potential of Cyclamen coum Mill

Virtual Screening of Antimicrobial Agents from Medicinal Plants

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