We investigate the spectrum structure of the eigenvalue problem { (4) ( ) = ( ), ∈ (0, 1); (0) = (1) = (0) = (1) = 0}. As for the application of the spectrum structure, we show the existence of solutions of the fourth-order boundary value problem at resonance {− (4) ( ) + 1 ( ) + ( , ( )) = ℎ( ), ∈ (0, 1); (0) = (1) = (0) = (1) = 0}, which models a statically elastic beam with both end-points being cantilevered or fixed, where 1 is the first eigenvalue of the corresponding eigenvalue problem and nonlinearity may be unbounded.