On the relationship between heart weights, fibrosis, and QRS duration

Mazzoleni, A; Curtin, Mary Ellen; Wolff, Richard D.; Reiner, Leopold; Somes, Grant W.

doi:10.1016/s0022-0736(75)80050-1

Cited by 48 publications

(33 citation statements)

References 6 publications

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“…It has also been noted that increased left ventricular size and muscle mass, myocardial fibrosis, and the involvement of the conduction system in ischemic areas prolong the duration of the basal QRS complex. 23 In a previous study, duration of basal QRS >100 ms was associated with lower ATP effectiveness applied to the right ventricle apex independently of left ventricle size, suggesting that longer conduction time was the mechanism responsible. 24 Gender differences in left ventricular size or hormonal differences have been suggested to influence ATP effectiveness, but the relationship has not been clearly established.…”

Section: Discussionmentioning

confidence: 87%

Efficacy of Anti-Tachycardia Pacing for Terminating Fast Ventricular Tachycardia in Japanese Implantable Cardioverter Defibrillator Patients

Watanabe

Inoue

Kashiwase

et al. 2014

Circ J

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Section: Discussionmentioning

confidence: 87%

Efficacy of Anti-Tachycardia Pacing for Terminating Fast Ventricular Tachycardia in Japanese Implantable Cardioverter Defibrillator Patients

Watanabe

Inoue

Kashiwase

et al. 2014

Circ J

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“…Therefore, the QRS width may have prognostic value in patients with HF and reduced LVEF [15,19,20]. However, the incidence of a prolonged QRS duration in the HF with preserved EF group was 13%, which was lower than that in the HF with reduced EF group.…”

Section: Discussionmentioning

confidence: 99%

QRS Prolongation in the Prediction of Clinical Cardiac Events in Patients with Acute Heart Failure: Analysis of Data from the Korean Acute Heart Failure Registry

et al. 2013

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Objectives: A prolonged QRS duration has been associated with an unfavorable prognosis in chronic compensated heart failure (HF). However, its predictive value during an admission for acute HF is limited, even in HF with a preserved ejection fraction (EF). The purpose of this study was to evaluate the prognostic utility of the QRS duration in acute HF. Methods: Analyses were performed using data from 1,489 patients with a 2-year follow-up. The patients were selected from the Korean Acute Heart Failure Registry and were divided into three groups according to QRS duration (≤80, 81-119 or ≥120 ms). The all-cause mortality and readmission for HF were assessed. Results: During the study period, 774 primary events occurred (359 deaths and 415 HF). The event frequencies were higher in patients with a prolonged QRS duration. The increased risk associated with the QRS duration was also demonstrated after adjustment for cardiac outcome variables. The prognostic significance of the QRS duration was demonstrated in patients with reduced EF but not in those with a preserved EF. Conclusions: A prolonged QRS duration could be a significant predictor of the 2-year cardiac outcome in patients with acute HF, particularly in those with a reduced EF.

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“…Mazzoleni et al reported a correlation between myocardial fibrosis and prolonged QRS duration. 44 Furthermore, Yamaji et al found a relationship between the development of AF and marked fibrosis of the LV in HCM. 45 In the present series, both the interventricular septal wall thickness and LV mass index were significantly greater in the AF group than in the SR group.…”

Section: Discussionmentioning

confidence: 99%

A985G Polymorphism of the Endothelin-2 Gene and Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy

Nagai

Ogimoto

Okayama

et al. 2007

Circ J

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On the relationship between heart weights, fibrosis, and QRS duration

Cited by 48 publications

References 6 publications

Efficacy of Anti-Tachycardia Pacing for Terminating Fast Ventricular Tachycardia in Japanese Implantable Cardioverter Defibrillator Patients

Efficacy of Anti-Tachycardia Pacing for Terminating Fast Ventricular Tachycardia in Japanese Implantable Cardioverter Defibrillator Patients

QRS Prolongation in the Prediction of Clinical Cardiac Events in Patients with Acute Heart Failure: Analysis of Data from the Korean Acute Heart Failure Registry

A985G Polymorphism of the Endothelin-2 Gene and Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy

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