On the Road to Precision Medicine: Magnetic Systems for Tissue Regeneration, Drug Delivery, Imaging, and Theranostics

Abstract

Magnetic systems have always been considered as attractive due to their remarkable versatility [...]

Efficient Chlorostannate Modification of Magnetite Nanoparticles for Their Biofunctionalization

“…Altogether, these facts suggest better binding of the mAb-FA antibody with MNP-SnCl(DMF)-mAb-FA, possibly due to the lower hydrolysis rate of SnCl2 in DMF. It should be noted that the developed magnetic IC metrology could be useful for the investigation of many other functionalized magnetic nanoparticles, which are extensively studied, for example, for targeted hyperthermia treatments of cancer [44], the isolation and identification of circulating tumor cells [45], the diagnosis and treatment of cardiovascular diseases [46], and magnetic systems for personalized and precision medicine [47], etc. In addition, studies like those discussed above on the interaction of FAconju- It should be noted that the developed magnetic IC metrology could be useful for the investigation of many other functionalized magnetic nanoparticles, which are extensively studied, for example, for targeted hyperthermia treatments of cancer [44], the isolation and identification of circulating tumor cells [45], the diagnosis and treatment of cardiovascular diseases [46], and magnetic systems for personalized and precision medicine [47], etc.…”

“…It should be noted that the developed magnetic IC metrology could be useful for the investigation of many other functionalized magnetic nanoparticles, which are extensively studied, for example, for targeted hyperthermia treatments of cancer [44], the isolation and identification of circulating tumor cells [45], the diagnosis and treatment of cardiovascular diseases [46], and magnetic systems for personalized and precision medicine [47], etc. In addition, studies like those discussed above on the interaction of FAconju- It should be noted that the developed magnetic IC metrology could be useful for the investigation of many other functionalized magnetic nanoparticles, which are extensively studied, for example, for targeted hyperthermia treatments of cancer [44], the isolation and identification of circulating tumor cells [45], the diagnosis and treatment of cardiovascular diseases [46], and magnetic systems for personalized and precision medicine [47], etc. In addition, studies like those discussed above on the interaction of FAconjugated nanoparticles with other bio and chemical objects are of great interest for various applications, such as the development of targeted cancer contrast agents for MRI [48] or biosensors for preventive medicine [49], the adsorption of unfavorable chemical compounds and biological pollutants [50], and many others.…”

Sonosensitive Cavitation Nuclei—A Customisable Platform Technology for Enhanced Therapeutic Delivery

“…Stimuli-responsive drug delivery systems represent a potential solution to this problem as they are minimally invasive yet enable deep tissue penetration. While many stimuli can be utilized (e.g., light [7], heat [8], or magnetic fields [9]), this review will primarily focus on ultrasound-mediated drug delivery and its progress towards clinical translation. The ability of ultrasound to enhance therapeutic delivery is due primarily to a physical effect known as cavitation, defined here as the nucleation, oscillation, collapse, or other excitation of gas cavities (bubbles) in a fluid due to sound pressure changes [10].…”