On the validity of using sympathomimetic drops in the treatment of habitually excessive tension of accommodation

Воронцова, Т. Н.; Brzhesky, V.V.

doi:10.21516/2072-0076-2016-9-4-80-89

ROJ

2016

DOI: 10.21516/2072-0076-2016-9-4-80-89

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On the validity of using sympathomimetic drops in the treatment of habitually excessive tension of accommodation

Т. Н. Воронцова¹,

V.V. Brzhesky²

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Cited by 3 publications

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The effect of phenylephrine hydrochloride 2.5 % and sodium hyaluronate solution on visual functions and accommodation in children with myopia and its local tolerability

Тарутта

Milash

et al. 2022

Rossijskij oftalʹmologičeskij žurnal

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Purpose: to evaluate visual functions, accommodation, and local tolerance in children instilled with Phenylephrine hydrochloride 2.5 % and sodium hyaluronate solution (Stelphrin Supra). Material and methods. 30 children (60 eyes) aged 8 to 12 (ave. 10.04 ± 0.24) with low (28 eyes) and moderate (32 eyes) myopia (ave. -2.96 ± 0.17 D) were tested. Refractometry, subjective and objective accommodation, optical biometry, anterior corneal surface examination, Norn test, and polling were performed prior to one-time instillation, 30 minutes after it, and after 1 month of daily bedtime instillations of Stelphrin Supra. Results. We noted a significant decrease in the tone of accommodation in the open field by 90 % from the initial value, an approximation of the nearest point of clear vision by 27 %, an increase in the volume of absolute accommodation by 57 % and the objective amplitude of accommodation by 20 %, which indicates an increase in the accommodation ability. The pupil width increased 30 minutes after a single instillation of Stelphrin Supra, which coincided with an increase in the relative accommodation reserve by 25 % from the initial one. After a month, the pupil width significantly decreased, and the positive relative accommodation reserve decreased to a level only 12 % higher than the original one. Tear film break time significantly increased by 0.89 sec, singular spot stainings disappeared in 2 out of 6 patients, lacrimation — in 6 out of 10, pain — in 1 out of 2, blurring in 4 out of 6, feeling of “sand” — in 7 out of 9 patients who had these symptoms before instillations. Conclusion. Regular instillations of Stelphrin Supra reduce the habitual tone of accommodation, increase the accommodation ability, and improve the condition of the eye surface.

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The effect of phenylephrine hydrochloride 2.5 % and sodium hyaluronate solution on visual functions and accommodation in children with myopia and its local tolerability

Тарутта

Milash

et al. 2022

Rossijskij oftalʹmologičeskij žurnal

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Analysis of the therapeutic effect of Midrimax® on accommodation overstrain in patients with orthokeratological correction

Makhova¹

2022

Rossijskij oftalʹmologičeskij žurnal

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Purpose: a year-long study of the accommodative function of the eye in patients with orthokeratologic (OK) correction, and the analysis of the therapeutic effect of the drug Midrimax® on accommodation overstrain in patients with OK lenses.Material and methods. The study group included 88 patients (176 eyes) with progressive myopia and OK lenses. The control group included 108 patients (216 eyes) who had optical correction with monofocal glasses and soft contact lenses. During the year, the accommodative function of patients of these two groups was studied using a Speedy-I Accommodograph that involved the calculation of accommodative coefficients: the coefficient of accommodative response and the coefficient of accommodative microfluctuations (CMF). The accommodographic examination in the study group was conducted before wearing OK lenses, after 1 month, 6 months and a year of wearing OK lenses. In the control group, the study of accommodation was carried out after 6 and 12 months. To assess the nature of the effect of Mydrimax® on accommodation overstrain, 70 children (140 eyes) with OK correction and varying degrees of accommodation overstrain were examined. A control group and a study group of 35 people (70 eyes) each were formed. In the study group, Mydrimax® was instilled daily before going to bed, 2 drops in each eye for 30 days. The study of accommodation on the Speedy-i accommodograph was conducted before treatment and after 30 days of treatment.Results. Before wearing OK lenses, 50.5 % had normal accommodative function, 33 % revealed lack of accommodation and only 16.5 % had various degrees of accommodation overstrain. After 6 months of using OK lenses, the accommodation pattern changed: 33.5 % of patients retained normal accommodation function, in 15.5 % of cases accommodation insufficiency decreased, but the number of patients (51.0 %) with accommodation overstrain of varying degrees increased. During the next 6 months of wearing OK lenses, the state of accommodation practically did not change: 39.5 % retained normal accommodative function, 10.5 % had insufficient accommodation and 49.5 % accommodation overstrain. The course of treatment with Mydrimax® for 30 days in patients with OK correction was effective at any degree of accommodation overstrain.Conclusion. The use of OK lenses stimulates accommodation by reducing the number of patients with accommodation insufficiency and increasing the number of patients with accommodation overstrain. The use of Mydrimax® for a course of 30 days is effective in patients with OK correction at any degree of accommodation overstrain.

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Differential Reorganization of Structural Elements of the Iridociliary and Perenticular Zones in the Hydrodynamic Blocks Formation

Щуко

Новожилова

Розанова

et al. 2021

Acta biomedica scientifica

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Резюме Обоснование. Ключевым звеном патогенеза закрытоугольной глаукомы является формирование структурных блоков, инициирующих нарушение гидростатического равновесия. Однако при равных параметрах глазного яблока, состояния путей оттока, уровень внутриглазного давления и гидродинамика глаза могут иметь принципиальные различия. Было предположено, что формирование гидродинамических блоков у пациентов с гиперметропией может быть инициировано уже в молодом возрасте процессами избыточной аккомодации, которые усугубляются физиологическим старением, сопровождающимся формированием пресбиопии. Цель исследования: выяснение факторов, провоцирующих и усугубляющих процессы формирования патологических изменений гидродинамики глаза, у пациентов старшего возраста с гиперметропией. Материалы и методы. Проведено всестороннее исследование переднего отрезка глаза у 80 пациентов в возрасте 45-60 лет с гиперметропической рефракцией. Оценка структурных девиаций проводилась с использованием ультразвуковой биомикроскопии и интерактивной Шеймпфлюг-регистрации переднего отрезка глаза («Pentacam HR», Oculus, США) с расчётом параметров передней и задней камеры глаза и коэффициента Lowe. Тонометрия и тонография проводилась на электронном тонографе «Mentor» (Tecnar Ophthasonic, США). Результаты и заключение. Совокупность результатов исследования 80 пациентов с гиперметропией была обработана с помощью кластерного анализа, по результатам, которого выявлена значительная и статистически значимая неоднородность для трёх кластеров. Сравнительный и регрессионный анализ установил, что преобразование параметров и положения внутриглазных структур исходно и в условиях нагрузочной пробы у лиц первого и третьего кластеров сопровождалось нарушением гидродинамики глаза с преобладающим включением, соответственно, лентикулярного или иридоцилиарного компонента. Изменения, выявленные у пациентов второго кластера, отличались сбалансированными умеренными изменениями структурных взаимоотношений и отсутствием клинически значимого повышения внутриглазного давления.

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On the validity of using sympathomimetic drops in the treatment of habitually excessive tension of accommodation

Cited by 3 publications

References 0 publications

The effect of phenylephrine hydrochloride 2.5 % and sodium hyaluronate solution on visual functions and accommodation in children with myopia and its local tolerability

The effect of phenylephrine hydrochloride 2.5 % and sodium hyaluronate solution on visual functions and accommodation in children with myopia and its local tolerability

Analysis of the therapeutic effect of Midrimax® on accommodation overstrain in patients with orthokeratological correction

Differential Reorganization of Structural Elements of the Iridociliary and Perenticular Zones in the Hydrodynamic Blocks Formation

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