Onchocerciasis in Tigray

Terranova, Margherita; Padovese, Valeska; Klaus, Sidney N.; Morrone, Andrea

doi:10.1111/j.1365-4632.2007.03472.x

Cited by 5 publications

(2 citation statements)

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“…The REMO carried out in Ethiopia involving six regions of the country indicated, all the six regions were endemic for onchocerciasis, and four out of the six had areas that were meso-or hyperendemic to onchocerciasis. Particularly the disease is widespread in western Ethiopia extending from the Takazi valley in the northwest to the Omo valley in the southwest in varying levels of endemicity (De Sole and Walton 1976;Zein 1986;Gundersen et al 1988;Tatichef et al 1987;Terranova et al 2007). Currently more than 10 million Ethiopians are at risk of onchocerciasis and three million are infected.…”

Section: Introductionmentioning

confidence: 99%

Parasitological and clinico-epidemiological features of onchocerciasis in West Wellega, Ethiopia

et al. 2011

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Onchocerciasis is a disease of public health and socio-economic importance in Ethiopia. The aim of this study was to assess parasitological and clinico-epidemiological features of onchocerciasis in the Anfilo District, West Wellega, prior to implementation of Community Directed Treatment with Ivermectin (CDTI) to generate epidemiological and parasitological data for use in control program of the disease and subsequent evaluation of CDTI. A cross-sectional study was conducted in Anfilo District of West Wellega zone during a period of 1 month: from midAugust to mid-September 2006. Data on socio-demographic characteristics were collected using a standardized questionnaire prepared for this purpose. All persons were examined clinically for skin signs and symptoms of onchocerciasis. Two skin snips, one from each side of the gluteal fold were taken using blood lancet and sterilized razor blade and examined for microfilaria. All data were categorized, coded, entered in a data base and analyzed using SPSS version 15.0. for windows. A total of 1114 individuals C15 years were examined for microfilariae (mf) of Onchocerca volvulus and onchocercal skin disease (OSD). The prevalence of onchocercal (mf) carrier was 74.8% (833/1114). In both genders, the prevalence of onchocerciasis showed direct correlations with the age of individuals (R 2 = 0.79, P \ 0.05). The infection rate varied with the occupation of the study subjects, with preponderance among farmers. Among the subjects with onchocerciasis, the mf density ranged from 1.0 to 711.0 per mg of skin snip with a mean density (SD) and median values of 32.1 (61.5) and 10.4 respectively. The overall community microfilariae load (CMFL), the most sensitive parasitological indicator of onchocerciasis was 19.6. The pervasiveness of OSD among the study subjects was 26.4%. OSD was more frequent in males (32.4%) than their female counterparts (20.8%, P \ 0.05). The overall prevalence of onchocercal nodule carrier, the symptom opted for determining the community-wide prevalence of onchocerciasis was 12.1%. Leopard skin, the proxy of longstanding infection of onchocerciasis in the community, was also relatively high (19.1%). The abundance of mf in skin would definitely lead to high transmission potential in the Anfilo District. The situation in the Anfilo District should call for continued CDTI, owing to success of similar recommendations for such programmes in other parts of the country and elsewhere.

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Section: Introductionmentioning

confidence: 99%

Parasitological and clinico-epidemiological features of onchocerciasis in West Wellega, Ethiopia

et al. 2011

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“…Diethylcarbamazine containing cream can be applied on a very limited skin area expected to be microfilaria-loaded. Itchy papular rash can be read 24-48 h after application in positive cases (Terranova et al 2007). Ivermectin is the drug of choice (Osei-Atweneboana et al 2007).…”

Section: Onchocerca Volvulusmentioning

confidence: 99%

Parasitic infections and myositis

et al. 2011

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Infectious myositis may be caused by a wide variety of bacterial, fungal, viral, and parasitic agents. Parasitic myositis is most commonly a result of trichinosis, cystericercosis, or toxoplasmosis, but other parasites may be involved. A parasitic cause of myositis is suggested by history of residence or travel to endemic area and presence of eosinophilia. The diagnosis of parasitic myositis is suggested by the clinical picture and radiologic imaging, and the etiologic agent is confirmed by parasitologic, serologic, and molecular methods, together with histopathologic examination of tissue biopsies. Therapy is based on the clinical presentation and the underlying pathogen. Drug resistance should be put into consideration in different geographic areas, and it can be avoided through the proper use of anti-parasitic drugs.

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Helminth infestations

Weedon

2010

Weedon's Skin Pathology

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Onchocerciasis in Tigray

Cited by 5 publications

References 5 publications

Parasitological and clinico-epidemiological features of onchocerciasis in West Wellega, Ethiopia

Parasitological and clinico-epidemiological features of onchocerciasis in West Wellega, Ethiopia

Parasitic infections and myositis

Helminth infestations

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