One step protocol and green synthesis of 2-N,N-dimethylamino-3-alkyl(aryl)-2-oxido-1- hydro-2-benzo[1,3,2]diazaphosphinine-4-one derivatives

Abstract

ABSTRACT. 2-N,N-dimethylamino-2-oxido-3-alkyl(aryl)-1-hydro-2-benzo[1,3,2]diazaphosphinin-4-one (2) derivatives are synthesized by one pot reaction by reacting equimolar quantities of anthranilic acid, primary amine, and N,N-dimethylphosphoramic dichloride under reflux of ethanol with good yields. The structure of the compounds were established on the basis of their infrared, nuclear magnetic resonance spectral data (1H NMR, 13C NMR and 31P NMR), mass spectrometry, and elemental analysis.
 
 KEY WORDS: Anthranilic acid, N,N-Dimethylphosphoramic dichloride, Diazaphosphinine
 Bull. Chem. Soc. Ethiop. 2022, 36(4), 859-864. 
 
 DOI: https://dx.doi.org/10.4314/bcse.v36i4.11