One versus two embryo transfer after IVF and ICSI: a randomized study

Martikainen, Hannu; Tiitinen, Aila; Tomás, Cǎndido; Tapanainen, Juha S.; Orava, Mauri; Tuomivaara, Leena; Vilska, Sirpa; Hydén-Granskog, Christel; Hovatta, Outi

doi:10.1093/humrep/16.9.1900

Cited by 313 publications

(200 citation statements)

References 11 publications

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“…The study presented here used exclusively day 5 embryos and clearly demonstrates that acceptable pregnancy rates can be achieved using single embryo transfers in a relatively unselected population of IVF patients. This study confirms those conducted previously (Martikainen et al, 2001;Salumets et al, 2003;Tiitinen et al, 2001;Vilska et al, 1999) using day 3 embryos. Only one study ) has included cumulative pregnancy rate but unfortunately the data did not include the cumulative rate for those patients having two embryos transferred in their stimulated cycle.…”

Section: Discussionsupporting

confidence: 93%

Single Embryo Transfer in IVF to Prevent Multiple Pregnancies

Catt¹,

Wood

Henman

et al. 2003

Twin res.

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Section: Discussionsupporting

confidence: 93%

Single Embryo Transfer in IVF to Prevent Multiple Pregnancies

Catt¹,

Wood

Henman

et al. 2003

Twin res.

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“…Several randomized controlled trials in Europe have demonstrated that eSET significantly diminishes twin gestations and yields comparable live birth rates in good prognosis patients [12,13].…”

Section: Introductionmentioning

confidence: 99%

Age-related success with elective single versus double blastocyst transfer

Friedman

Davis

Lathi

et al. 2008

Fertility and Sterility

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“…eSET was later performed on older women \36 years of age [26][27][28][29][30]. These studies found a decrease in the multiple gestation rate without a decrease in the pregnancy rate in each case.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of possible criteria for elective single embryo transfer

Sato

Fukuda

Kanamori

et al. 2010

Reprod Medicine & Biology

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Purpose A major problem of assisted reproductive technology (ART) is multiple gestation, which impacts neonatal and perinatal medicine. The literature contains a number of reports that elective single embryo transfer (eSET) is effective for the control of multiple pregnancies; however, to date, uniform criteria have not been established. Methods Using logistic regression analysis based on the results of ART in our department from January 2005 to July 2006, our eSET criteria were established. We conducted a comparative study of the clinical pregnancy rate, multiple gestation rate, and delivery rate before and after eSET (before-eSET and after-eSET groups, respectively). Results As a result of the analysis, our eSET criteria included all three of the following: (A) patient age B37, (B) previous IVF/ICSI trials B5, and (C) acquisition of two or more good-quality embryos. Based on our criteria, the after-eSET group was not found to have a decrease in the pregnancy rate; however, the multiple gestation rate decreased as compared to the before-eSET group. In addition, as a result of various evaluations of the eSET group, interesting findings were revealed. Conclusions In the after-eSET group, our eSET criteria achieved a decrease in the multiple pregnancy rate without a decrease in the pregnancy rate.

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One versus two embryo transfer after IVF and ICSI: a randomized study

Cited by 313 publications

References 11 publications

Single Embryo Transfer in IVF to Prevent Multiple Pregnancies

Single Embryo Transfer in IVF to Prevent Multiple Pregnancies

Age-related success with elective single versus double blastocyst transfer

Evaluation of possible criteria for elective single embryo transfer

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