2003
DOI: 10.1274/jmor.20.86
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Oocyte Maturation in Humans: the Potential Relevance to Reproductive Medicine

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“…Additionally, IVM might provide a valuable model for investigating the causes of meiotic aberrations and aneuploidies that are remarkably common in mature human oocytes. Finally, IVM might open the door to oocyte cryopreservation if the freeze storage of germinal vesicle (GV) stage oocytes avoids the problem of damaging the meiotic spindle of metaphase II (MII) stage oocytes 1 . Therefore, IVM is an important technique for assisted reproductive technology and deserves rigorous experimental evaluation to determine whether it is practicable in reproductive medicine.…”
Section: Introductionmentioning
confidence: 99%
“…Additionally, IVM might provide a valuable model for investigating the causes of meiotic aberrations and aneuploidies that are remarkably common in mature human oocytes. Finally, IVM might open the door to oocyte cryopreservation if the freeze storage of germinal vesicle (GV) stage oocytes avoids the problem of damaging the meiotic spindle of metaphase II (MII) stage oocytes 1 . Therefore, IVM is an important technique for assisted reproductive technology and deserves rigorous experimental evaluation to determine whether it is practicable in reproductive medicine.…”
Section: Introductionmentioning
confidence: 99%