Open-channel microfluidic chip based on shape memory polymer for controllable liquid transport

Ye, Wen-Qi; Liu, Xiaopeng; Ma, Ruofei; Yang, Chunguang; Xu, Zhang-Run

doi:10.1039/d3lc00027c

Cited by 8 publications

(6 citation statements)

References 24 publications

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“…Conventional microfluidic chips, such as glass chips, PDMS chips, and PMMA chips, are typically fabricated with planar Copyright 2023 Royal Society of Chemistry. 37 channels. However, these conventional designs fall short in replicating intricate fluidic models such as tissue development or vascular network simulation, which require a more realistic representation of the actual scenario.…”

Section: Fluid Manipulationmentioning

confidence: 99%

“…However, the inability to integrate valves and pumps in open channels is a common drawback, resulting in limited control over fluid flow. Xu's team 37 has developed a shape memory open-channel microfluidic chip utilizing ethylenevinyl acetate copolymer, where the microcolumns in the channels exhibit photothermal and magnetic responsiveness. With magnetic assistance, the bending angle and direction of the microcolumns can be adjusted through near-infrared light irradiation.…”

Section: Fluid Manipulationmentioning

confidence: 99%

“…In summary, researchers have developed a variety of shape memory microfluidic chips. The response time of these shape memory microfluidic chips typically ranges from 5 to 30 s, 4,9,37,54 with the shortest response time being as fast as 100 ms. 35 Increasing the temperature or improving the thermal conductivity of polymers can effectively shorten the response time of temperature-responsive SMPs. In addition, alternative triggering methods like near-infrared light triggering and electrical triggering can also be employed for more efficient activation.…”

Section: B Droplet Manipulationmentioning

confidence: 99%

“…36 (e) Liquid transport is controlled through the deformation of shape memory microcolumns in an open-channel microfluidic chip, enabling controllable liquid transportation. Reproduced with permission from Ye et al, Lab Chip 23(8), 2068-2074 (2023).Copyright 2023 Royal Society of Chemistry 37.…”

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confidence: 99%

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Shape-memory microfluidic chips for fluid and droplet manipulation

Ye,

Zhang,

2024

Biomicrofluidics

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Fluid manipulation is an important foundation of microfluidic technology. Various methods and devices have been developed for fluid control, such as electrowetting-on-dielectric-based digital microfluidic platforms, microfluidic pumps, and pneumatic valves. These devices enable precise manipulation of small volumes of fluids. However, their complexity and high cost limit the commercialization and widespread adoption of microfluidic technology. Shape memory polymers as smart materials can adjust their shape in response to external stimuli. By integrating shape memory polymers into microfluidic chips, new possibilities for expanding the application areas of microfluidic technology emerge. These shape memory polymers can serve as actuators or regulators to drive or control fluid flow in microfluidic systems, offering innovative approaches for fluid manipulation. Due to their unique properties, shape memory polymers provide a new solution for the construction of intelligent and automated microfluidic systems. Shape memory microfluidic chips are expected to be one of the future directions in the development of microfluidic technology. This article offers a summary of recent research achievements in the field of shape memory microfluidic chips for fluid and droplet manipulation and provides insights into the future development direction of shape memory microfluidic devices.

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Section: Fluid Manipulationmentioning

confidence: 99%

Section: Fluid Manipulationmentioning

confidence: 99%

Section: B Droplet Manipulationmentioning

confidence: 99%

mentioning

confidence: 99%

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Shape-memory microfluidic chips for fluid and droplet manipulation

Ye,

Zhang,

2024

Biomicrofluidics

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“…Microfluidic devices are small-scale systems that manipulate and control the flow of fluids at the micrometer scale. They are typically made up of channels, chambers, and valves that can be designed to perform various tasks, such as mixing, separating, and analyzing fluids [ 103 , 104 ]. Microfluidic devices are often used to perform complex chemical and biological assays, where precise control over the flow of fluids is essential for accurate and reliable results [ 105 , 106 ].…”

Section: Ai In Other Fields Related To Regenerative Medicinementioning

confidence: 99%

Artificial Intelligence in Regenerative Medicine: Applications and Implications

Nosrati,

Nosrati

2023

Biomimetics

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The field of regenerative medicine is constantly advancing and aims to repair, regenerate, or substitute impaired or unhealthy tissues and organs using cutting-edge approaches such as stem cell-based therapies, gene therapy, and tissue engineering. Nevertheless, incorporating artificial intelligence (AI) technologies has opened new doors for research in this field. AI refers to the ability of machines to perform tasks that typically require human intelligence in ways such as learning the patterns in the data and applying that to the new data without being explicitly programmed. AI has the potential to improve and accelerate various aspects of regenerative medicine research and development, particularly, although not exclusively, when complex patterns are involved. This review paper provides an overview of AI in the context of regenerative medicine, discusses its potential applications with a focus on personalized medicine, and highlights the challenges and opportunities in this field.

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Peristome‐Mimetic Surfaces Fabricated by Nanosecond Laser for Unidirectional Liquid Spreading

Wan,

Yang,

Zhang

et al. 2024

Adv Eng Mater

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Unidirectional liquid transport, which operates without external energy input, has garnered remarkable interests in the global energy sector. A crucial breakthrough in this field involves understanding how liquids spread on the peristome surface of Nepenthes alata. This study, inspired by the microstructural traits of the Nepenthes peristome, has brought about the development of a biomimetic surface on metal substrates using nanosecond laser processing on inclined bases. This process replicates the natural peristome’s microstructure, which allows for controlled liquid spread on the surface. The research also examines how wettability influences unidirectional liquid spread. Additionally, it involves adjusting the microstructure parameters on the biomimetic surface, which leads to variations in edge curvature and microcavity wedge angles. More importantly, this study comprehensively investigates the relationship between these structural changes and the phenomenon of unidirectional liquid transport. The findings suggest that altering edge curvature and micro‐cavity wedge angles can manage the directional spread of liquids. The optimized surface, with ideal curvature and wedge angles, achieves liquid movement speeds up to 12.03mm/s. This represents a notable improvement, 2.2 and 2.7 times faster than the original structure, respectively. These findings provides valuable insight into the design of energy‐independent unidirectional liquid spreading surfaces on metal substrates.This article is protected by copyright. All rights reserved.

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Open-channel microfluidic chip based on shape memory polymer for controllable liquid transport

Abstract: Open microfluidics has attracted increasing attention over the last decade because of its flexibility and simplicity with respect to cell culture and clinical diagnosis. However, traditional valves and pumps are...

Cited by 8 publications

References 24 publications

Shape-memory microfluidic chips for fluid and droplet manipulation

Shape-memory microfluidic chips for fluid and droplet manipulation

Artificial Intelligence in Regenerative Medicine: Applications and Implications

Peristome‐Mimetic Surfaces Fabricated by Nanosecond Laser for Unidirectional Liquid Spreading

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